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Pathways to Cardiovascular Disease Prevention (DCRI Central and Statistical Coordinating Center)

Cardiovascular Diseases Clinical Trial

Official title:
Pathways to Cardiovascular Disease Prevention and Impact of Specialty Referral in Underrepresented Racial/Ethnic Minorities With HIV (Coordinating Center)

Clinical Trial Summary

The goal of this research is to generate evidence-based recommendations for the management of cardiovascular disease (CVD) risk in People Living with HIV (PLWH). The overall objectives of this application are to demonstrate the effect of cardiology referral on CVD outcomes in a racially/ethnically diverse cohort of PLWH, and to generate qualitative data with which to develop of a future intervention. Our central hypothesis is that cardiology referral reduces incident CVD events in underrepresented racial/ethnic minority (URM) populations with HIV compared to nonreferral. Our hypothesis has been formulated based on our own work identifying that race and provider specialty impact cardiovascular risk management. The rationale for our research is that, once it is known how URM populations with HIV access cardiology referrals, and the impact on CVD outcomes, an intervention can be appropriately designed resulting in new and innovative approaches to the management of URM PLWH at elevated CVD risk.

Clinical Trial Description

Aim 1. To identify factors associated with cardiology referral in under-represented racial and ethnic minority (URM) populations with HIV and elevated cardiovascular risk Aim 2. To evaluate the association between cardiology referral and CVD outcomes in under-represented racial and ethnic populations with HIV and elevated cardiovascular risk Sub-Aim 2a. To evaluate the association between cardiology referral and guideline-based CVD prevention measures in URM populations with HIV and elevated CVD risk Note: Aims 1 and 2-retrospective analysis with anticipated 8000 EHR records to be reviewed. Aim 3. To identify facilitators and barriers to optimal CVD prevention ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04025125
Study type Observational
Source Duke University
Contact
Status Completed
Phase
Start date October 29, 2019
Completion date July 30, 2022
View Details
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