Cardiovascular Diseases Clinical Trial
Official title:
A 4-week Consumption of Light or Dark Roast Unfiltered (Turkish) Coffee Affects Cardiovascular Risk Parameters of Homocysteine and Cholesterol Concentrations in Healthy Subjects: A Randomized Crossover Clinical Trial
Purpose/Objective: The aim of this study is to investigate the impact of boiled unfiltered
(Turkish) coffee consumption on the plasma cardiovascular risk parameters of healthy
subjects. The study also explores whether two unfiltered boiled (Turkish) coffee beverages
that differ in content due to different roasting degrees will differentially affect
cardiovascular biomarkers.
Methods: In this crossover intervention study, healthy, nonsmoking, habitual Turkish coffee
drinkers (n=28) were randomized to consume at least 3 cups of Light (LR) or Dark (DR) roast
Turkish coffee brews per day for 4 weeks after a washout period (WO) of 2 weeks. Subsequent
to each coffee abstinence period, both groups received the alternative intervention. After
the first WO and the coffee intervention periods, anthropometric measures, blood pressure,
heart rate and 13 biochemical parameters were collected and dietary records were completed.
Background: Considerable controversy exists regarding the link between coffee consumption and
cardiovascular disease (CVD) risk. It has been shown that different coffee preparation and
brewing methods influence the concentration of compounds present in the final coffee brew.
Unlike coffee traditionally consumed in the western world, Turkish coffee is not drip
filtered, but rather its method of preparation involves slowly boiling water that is mixed
with thinly ground coffee beans. This style of preparation results in a greater amount of
biologically active components (caffeine and diterpenes) remaining in the liquid. In addition
to preparation styles, roasting process greatly affects the chemical composition of the
coffee. Coffee types differing in content of major constituents differ with regard to
cardiovascular health effects.
Purpose/Objective: The aim of this study is to investigate the impact of boiled unfiltered
(Turkish) coffee consumption on the plasma cardiovascular risk parameters of healthy
subjects. The study also explores whether two unfiltered boiled (Turkish) coffee beverages
that differ in content due to different roasting degrees will differentially affect
cardiovascular biomarkers.
Methods: In this crossover intervention study, healthy, nonsmoking, habitual Turkish coffee
drinkers (n=28) were randomized to consume at least 3 cups of Light (LR) or Dark (DR) roast
Turkish coffee brews per day for 4 weeks after a washout period (WO) of 2 weeks. Subsequent
to each coffee abstinence period, both groups received the alternative intervention. After
the first WO and the coffee intervention periods, anthropometric measures, blood pressure,
heart rate and 13 biochemical parameters were collected and dietary records were completed.
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