Temperature and Mortality

Cardiovascular Diseases Clinical Trial

Official title:

Impact of Increasing Temperature Over the Coming Century on Mortality From CVD and Stroke

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03259100
• Other study ID #: CDC and IPCC
• Status: Completed
• Phase: N/A
• First received: August 19, 2017
• Last updated: August 22, 2017
• Start date: January 1, 2011
• Est. completion date: February 1, 2013

Study information

• Verified date: August 2017
• Source: Chinese Academy of Sciences
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators evaluated the spatial association between, cardiovascular diseases (CVD) and stroke mortality rate with average ambient temperature (Ta) , and then used this relationship to model future temporal trends in mortality from CVD and stroke till the end of century (2099) using different warming scenarios across the mainland USA.

Description:

the investigators used data on mortality rate (per 100,000 individuals) for CVD and stroke (between 2011 and 2013, age>35years) from the publicly available Centers for disease prevention and control (CDC) web site (www.cdc.gov). CVD mortality was defined as the number of deaths per 100,000 personyears due to circulatory causes (International Statistical Classification of Diseases, Tenth Revision, codes I00-I99).Oak Ridge National laboratory was the source of the ambient temperature data (http://www.daac.ornl.gov: files B01, B02 and C07).The investigators obtained data on prevalence of HTN (HTN was defined as systolic blood pressure (BP) of at least 140 mm Hg, self-reported use of antihypertensive treatment, or both) from county health rankings and roadmaps organisation (www.countyhealthrankings.org), which were estimated based on National Health and Nutrition Examination Survey in five two-year waves from 1999-2008 including 26,349 adults aged 30 years and older and from the Behavioral Risk Factor Surveillance System (BRFSS) from 1997-2009 including 1,283,722 adults aged 30 years and older.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 17000000
• Est. completion date: February 1, 2013
• Est. primary completion date: January 1, 2012
• Accepts healthy volunteers: No
• Gender: All
• Age group: 35 Years and older

Eligibility

Inclusion Criteria:

1. age>35 years

Exclusion Criteria:

Related Conditions & MeSH terms

• Cardiovascular Diseases

Intervention

Other:
• all the data collection have done by CDC.
In this study there was no intervention, just simple data collection via CDC.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Chinese Academy of Sciences

References & Publications (3)

Mazidi M, Speakman JR. Higher densities of fast-food and full-service restaurants are not associated with obesity prevalence. Am J Clin Nutr. 2017 Aug;106(2):603-613. doi: 10.3945/ajcn.116.151407. Epub 2017 May 31. — View Citation

Mohsen Mazidi& John R. Speakman. ambient particulate air pollution (PM2.5) is associated with the ratio of type 2 diabetes to obesity.Scientific Reports. DOI:10.1038/s41598-017-08287-1

Speakman JR, Heidari-Bakavoli S. Type 2 diabetes, but not obesity, prevalence is positively associated with ambient temperature. Sci Rep. 2016 Aug 1;6:30409. doi: 10.1038/srep30409. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	spatial association between, cardiovascular diseases (CVD) and stroke mortality rate with average ambient temperature	spatial association between, cardiovascular diseases (CVD) and stroke mortality rate with average ambient temperature	2011-2013

External Links

•   CDC website