Clinical Trials Logo

Clinical Trial Summary

The objective of this study is to investigate the effectiveness of air filtration at reducing personal-level exposures to fine particulate matter (PM2.5) and mitigating related cardiovascular (CV) health effects among older adults in a residential facility in a representative US urban location. We enrolled 40 nonsmoking older adults into a randomized double-blind crossover intervention study with daily CV health outcomes and PM2.5 exposure measurements. The study was conducted in a low-income senior living apartment building in downtown Detroit, Michigan. Participants were exposed to three 3-day scenarios separated by one-week washout periods: unfiltered ambient air (control), low-efficiency (LE) "HEPA-type", and high-efficiency (HE) "true-HEPA" filtered air using air filtration systems in the bedroom and main living space of each residence. The primary outcome was brachial blood pressure (BP). Secondary outcomes included noninvasive aortic hemodynamics and pulse wave velocity and heart rate variability. PM2.5 exposures were measured in the participants' residences as well as by personal-level monitoring.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03334565
Study type Interventional
Source Michigan State University
Contact
Status Completed
Phase N/A
Start date October 21, 2014
Completion date November 4, 2016

See also
  Status Clinical Trial Phase
Completed NCT05380167 - Efficacy Long-term Dietary Nitrate Consumption to Plasma Nitrite Conversion N/A
Recruiting NCT06235658 - Yoga in Older Cardiac Patients N/A
Completed NCT04291690 - The TARGET-EFT Randomized Clinical Trial N/A
Not yet recruiting NCT05536310 - TAVIS Registry - Trilogy Heart Valve System for Management of Patients With Aortic Valve Disease
Completed NCT04778891 - The Impact of Comprehensive Medication Management Services on Clinical Outcomes in Patients With Cardiovascular Diseases at Primary Care Level N/A
Recruiting NCT03895541 - Noninvasive Elastography Evaluation of Myocardial Stiffness in Elderly Patients With Isolated Diastolic Heart Failure: New Diagnostic Tool? N/A
Not yet recruiting NCT05617196 - Virtual PREHAB Study for Patients Undergoing TAVI N/A
Recruiting NCT06336070 - Metabolic Flexibility and Autonomic Control After Muscle Power vs Metabolic Power Training in Postmenopausal Oncological Women: the POWER Health Study N/A
Completed NCT05888506 - Ketone Ester Supplementation and Nocturnal Blood Pressure N/A