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Variation of Aortic Compliance Related to Exercise Training With or Without Supervised Sessions — ACT  

Cardiovascular Disease Clinical Trial

Official title:
Exercise Training in Patients With Cardiovascular Risk: Predictability of Aortic Compliance Normalization

Clinical Trial Summary

Many conditions and cardiovascular diseases (including stroke) are better managed with regular exercise training. The expected effects are partial reversal of adverse effects on heart and blood vessel structure and function, improved glycemic, tension and weight control.

Physiologically, the aorta maintains low left ventricular after-load, promotes optimal sub-endocardial coronary blood flow, and transforms pulsatile into laminar blood flow. Increased aortic stiffness may ultimately contribute to left ventricular dysfunction. Regular exercise training is likely to decrease the pulse wave velocity (a measure of the aortic compliance). Some subjects seem more responsive than others, and they may not expect the same benefit of exercise training. To the best of our knowledge, this has not been explained yet.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01939080
Study type Interventional
Source University Hospital Center of Martinique
Contact Armelle JEAN-ETIENNE, MD
Email Armelle.Jean-Etienne@chu-fortdefrance.fr
Status Recruiting
Phase N/A
Start date April 2013
Completion date August 2018
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