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NCT00530595 Clinical Trial

Effects of Angiotensin Receptor Antagonist on Prohibiting Cardiovascular Events on Hemodialysis Patients

Cardiovascular Disease Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00530595
Other study ID # S-01
Secondary ID
Status Completed
Phase N/A
First received September 13, 2007
Last updated September 14, 2007

Study information
Verified date September 2007
Source Saitama Medical University
Contact n/a
Is FDA regulated No
Health authority Japan: Institutional Review Board
Study type Interventional

Clinical Trial Summary

Cardiovascular disease is a leading cause of mortality in patients on hemodialysis therapy (HD), accounting for 30 to 50% of all death. Although angiotensin receptor blockers (ARBs) are effective for patients with diabetes and chronic kidney disease in reducing or preventing cardiovascular diseases, there has been no decisive study that demonstrated treatment with ARBs is effective in patients on HD.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 30 Years to 80 Years
Eligibility Inclusion Criteria:

- 30 to 80 years of age

- Receiving hemodialysis at least 12 months and less than 5 years

- Pre-dialysis systolic blood pressure was more than 160 mmHg, or more than 150 mmHg if the patients received antihypertensive agents.

Exclusion Criteria:

- Use of angiotensin receptor blocker or angiotensin converting enzyme inhibitor

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• candesartan or valsartan or losartan

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Saitama Medical University
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