Clinical Trials Logo

Clinical Trial Summary

Although inotropes have a favorable effect on central hemodynamics in patients with heart failure, their effect on renal hemodynamics is incompletely defined. The purpose of this study is to evaluate the efficacy of a 75 min intravenous infusion of levosimendan compared to a 75 min infusion of dobutamine on renal hemodynamics and function in patients with chronic heart failure and signs of cardiorenal syndrome. The investigators hypothesis is that patients treated with levosimendan will show greater increases in renal blood flow and glomerular filtration rate (GFR) than those treated with dobutamine.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02133105
Study type Interventional
Source Göteborg University
Contact
Status Completed
Phase Phase 3
Start date April 2014
Completion date May 2017

See also
  Status Clinical Trial Phase
Suspended NCT04589065 - SCD for CRS in Congestive Heart Failure (CHF) (No Left Ventricular Assist Device) N/A
Not yet recruiting NCT02238093 - Cardiorenal Syndrome in End-Stage Kidney Disease N/A
Completed NCT01265615 - Paricalcitol Versus Calcitriol for the Management of Renocardiac Syndrome in Renal Transplant Patients Phase 4
Completed NCT03039959 - Predictive Value of Renal Venous Flow Profiles for Adverse Outcomes in Right Heart Failure
Suspended NCT03836482 - Selective Cytopheretic Device (SCD) Trial N/A
Recruiting NCT06111768 - Sodium-Glucose Cotransporter-2 Inhibitor for Acute Cardiorenal Syndrome: A Feasibility Study Phase 2
Withdrawn NCT02644057 - Dobutamaine Versus Milrinone in Cardiorenal Syndrome Phase 2
Completed NCT01570153 - Biomonitoring and Cardiorenal Syndrome in Heart Failure(BIONICS-HF) Trial N/A
Completed NCT05927285 - Effect on Kidney Function Recovery Guiding Decongestion With VExUS in Patients With Cardiorenal Syndrome 1 N/A
Completed NCT03183323 - Implementation of Telerehabilitation In Support of HOme-based Physical Exercise for Heart Failure N/A
Completed NCT04917497 - Levosimendan Infusion in Critically Ill Patients With Cardiogenic Shock
Completed NCT04227977 - Volume Optimization Incorporating Negative Pressure Diuresis in Heart Failure (VOID-HF) N/A
Recruiting NCT03684876 - Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery
Completed NCT04393493 - The Effect in Renal Function on Patients With Type 1 Cardiorenal Syndrome Treated With Two Strategies of Furosemide. Phase 2
Completed NCT04145635 - The Aortix CRS Pilot Study N/A
Completed NCT02372292 - Value of Renal Vascular Doppler Sonography in Management of Decompensated Heart Failure N/A
Terminated NCT01364636 - Accuracy of Urinary NGAL in Predicting CardioRenal Syndrome in Acute Heart Failure at Emergency - CYNDERELA-HF Study
Completed NCT04116034 - Alfapump Direct Sodium Removal (DSR) Feasibility Study N/A
Terminated NCT00348556 - Use of Nesiritide (BNP) in Kidney Function in Patients With Congestive Heart Failure (CHF) and Kidney Failure Phase 1/Phase 2
Completed NCT03753607 - Renal Venous Flow and Cardiac Surgery-associated Acute Kidney Injury