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NCT03534726 Clinical Trial

Edema and Fibrosis CMR Imaging in Cardiomyopathy

Cardiomyopathies Clinical Trial

Official title:
Edema and Fibrosis Cardiac Magnetic Resonance Imaging in Cardiomyopathy

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT03534726
Other study ID # 827516
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date February 1, 2018
Est. completion date January 31, 2026

Study information
Verified date April 2024
Source University of Pennsylvania
Contact n/a
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

7 Tesla MRI is a new magnetic field strength that has become available at Penn for cardiovascular MRI. This new scanner has potential to improve assessment of cardiovascular disease due to its increased signal-to-noise ratio, higher spatial resolution, and response to magnetic properties of tissue at high field. The purpose of this study is to assess the feasibility of 7 T CMR. Secondly, we wish to investigate its use, to improve clinical and research MRI. Altogether, 7 T may permit better clinical diagnosis of cardiomyopathy.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 13
Est. completion date January 31, 2026
Est. primary completion date January 31, 2025
Accepts healthy volunteers
Gender All
Age group 20 Years to 70 Years
Eligibility Inclusion Criteria: - Subjects between the ages of 20-70 years old Exclusion Criteria: - Advanced renal disease (estimated GFR rate < 30 mL/min) or hypersensitivity to gadolinium contrast agent. - Presence of cardiac pacemaker or implanted cardioverter defibrillator - Pregnancy - Inability to provide informed consent - Other contraindications to MRI (such as claustrophobia)

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• 7 T CMR
7 tesla MRI device

Locations
Country Name City State
United States University of Pennsylvania Philadelphia Pennsylvania

Sponsors (1)
Lead Sponsor Collaborator
University of Pennsylvania

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary ejection fraction 5 years
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