18F-FSPG PET/MRI or PET/CT Imaging of Cardiac Sarcoidosis or Inflammation

Status Terminated

Clinical Trial Summary

The investigators will evaluate the detection of cardiac sarcoidosis or inflammation using 18F-FSPG PET/MRI (or PET/CT for participants with metal implants).

Clinical Trial Description

PET/MRI scans will be performed with a whole-body PET/MR imaging system capable of simultaneous PET and MR imaging (SIGNA, GE Healthcare, Milwaukee, WI). Approximately 45-60 minutes after IV injection of 8 mCi of 18F-FSPG, PET emission scanning and MRI acquisition T1 weighted scanning will begin imaging both whole body and the heart. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03103490
Study type	Interventional
Source	Stanford University
Contact
Status	Terminated
Phase	Phase 2
Start date	August 2, 2017
Completion date	September 28, 2021

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03705884` - PET/MR Imaging In Patients With Cardiac Sarcoidosis	N/A
Recruiting	`NCT04017936` - Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis	Phase 2
Recruiting	`NCT06131112` - Macrophage PET/CT Imaging Using 64Cu-DOTATATE for the Diagnosis of Cardiac Sarcoidosis
Terminated	`NCT03923049` - Feasibility and Accuracy of Hybrid Magnetic Resonance and Positron Emission Tomography With 18F-Fluorodeoxyglucose in Diagnosing Cardiac Sarcoidosis	N/A
Not yet recruiting	`NCT05954507` - Evaluation of the Prognostic Value of PET/MRI in Cardiac Sarcoidosis	N/A
Recruiting	`NCT04737317` - Diagnostic Criteria in Cardiac Sarcoidosis
Recruiting	`NCT06409585` - Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
Recruiting	`NCT03057002` - UTSW HP [13-C] Pyruvate Injection in HCM
Completed	`NCT03599414` - CASPA: CArdiac Sarcoidosis in PApworth
Withdrawn	`NCT02812849` - Somatostatin Receptor Imaging in Cardiac Sarcoidosis
Completed	`NCT01729169` - Cardiac Sarcoidosis: FDG PET vs. Ga-DOTANOC PET	N/A
Completed	`NCT03549598` - d68Ga-DOTATATE PET/CT Assessment of Cardiac Sarcoidosis	Phase 4
Recruiting	`NCT04758650` - Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis	Phase 2
Recruiting	`NCT04206163` - Somatostatin Receptor Imaging in Acute Myocarditis and Cardiac Sarcoidosis	N/A
Recruiting	`NCT05499637` - [68Ga]Ga-PentixaFor PET/CT in Acute Myocardial Inflammation	Phase 2
Recruiting	`NCT03593759` - Cardiac Sarcoidosis Randomized Trial	Phase 3
Recruiting	`NCT05145023` - Development and Validation of a Health-related Quality of Life Tool for Patients With Cardiac Sarcoidosis
Enrolling by invitation	`NCT04774549` - Inflammatory Cardiomyopathy Bern Registry
Recruiting	`NCT03049254` - Mayo AVC Registry and Biobank
Completed	`NCT03746847` - PET Imaging in Patients With Suspected Cardiac Sarcoidosis