Post-CA Neuroprotection With Magnesium

Status Not yet recruiting

Clinical Trial Summary

The purpose of this pilot interventional study is to collect preliminary data on administering magnesium sulfate as a neuroprotective medication in patients who achieved Return of Spontaneous Circulation (ROSC) following Cardiac Arrest (CA). The primary aims are to assess the feasibility and safety of administering magnesium and measure serum markers of neuronal injury at prespecified time points in the post-cardiac arrest period. Because this is a pilot study with a limited sample size, the primary objective is to evaluate the precision and stability of the collected measures to inform the design and formal analysis in a larger trial.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Cardiac Arrest
Heart Arrest
Return of Spontaneous Circulation

Clinical Trial Details

NCT number	NCT06455514
Study type	Interventional
Source	NYU Langone Health
Contact	Anelly Gonzales
Phone	646-501-6923
Email	resuscitationlab@nyulangone.org
Status	Not yet recruiting
Phase	Phase 1
Start date	August 1, 2024
Completion date	April 1, 2026

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06048068` - Removing Surrogates' Uncertainty to Reduce Fear and Anxiety After Cardiac Events	N/A
Recruiting	`NCT05558228` - Accuracy of Doppler Ultrasound Versus Manual Palpation of Pulse in Cardiac Arrest
Completed	`NCT03685383` - Cytokine Adsorption in Post-cardiac Arrest Syndrome in Patients Requiring Extracorporeal Cardiopulmonary Resuscitation	N/A
Completed	`NCT04584645` - A Digital Flu Intervention for People With Cardiovascular Conditions	N/A
Completed	`NCT04619498` - Effectiveness of an Interactive Cognitive Support Tablet App to Improve the Management of Pediatric Cardiac Arrest	N/A
Not yet recruiting	`NCT05649891` - Checklists Resuscitation Emergency Department	N/A
Withdrawn	`NCT02352350` - Lactate in Cardiac Arrest	N/A
Completed	`NCT03024021` - Cerebral Oxymetry and Neurological Outcome in Therapeutic Hypothermia
Completed	`NCT02247947` - Proteomics to Identify Prognostic Markers After CPR and to Estimate Neurological Outcome
Completed	`NCT02275234` - Care After Resuscitation
Completed	`NCT01972087` - Simulation Training to Improve 911 Dispatcher Identification of Cardiac Arrest	N/A
Completed	`NCT01944605` - Intestinal Ischemia as a Stimulus for Systemic Inflammatory Response After Cardiac Arrest	N/A
Completed	`NCT01936597` - Prospective Study of 3 Phone Assistance Strategies to Achieve a Continuous Cardiac Massage	N/A
Active, not recruiting	`NCT01239420` - Norwegian Cardio-Respiratory Arrest Study
Completed	`NCT00878644` - Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-OH [Out of Hospital] Trial	Phase 3
Completed	`NCT00880087` - Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial	N/A
Completed	`NCT01191736` - Ultra-Brief Versus Brief Hands Only CPR Video Training With and Without Psychomotor Skill Practice	N/A
Completed	`NCT00729794` - Vasopressin, Epinephrine, and Steroids for Cardiac Arrest	Phase 3
Recruiting	`NCT00441753` - Cerebral Bloodflow and Carbondioxide Reactivity During Mild Therapeutic Hypothermia in Patients After Cardiac Arrest	N/A
Completed	`NCT00347477` - Fluid Shifts in Patients Treated With Therapeutic Hypothermia After Cardiac Arrest	Phase 3