Improving Outcomes in Cardiac Arrest With Inhaled Nitric Oxide

Status Recruiting

Clinical Trial Summary

Sudden cardiac arrest (CA) is a leading cause of death worldwide. CA claims the lives of an estimated 300,000 Americans each year. Despite advances in cardiopulmonary resuscitation (CPR) methods, only approximately 10% of adults with CA survive to hospital discharge, and up to 60% of survivors have moderate to severe cognitive deficits 3 months after resuscitation. Most of the immediate and post-CA mortality and morbidity are caused by global ischemic brain injury. The goal of this grant application is to test the hypothesis that resuscitation from cardiac arrest can be improved by improving cerebral oxygenation through inhalation of nitric oxide. This strategy will also improve the chances of return of spontaneous circulation (ROSC), improve short-term survival and neurologic outcome.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04134078
Study type	Interventional
Source	Stony Brook University
Contact	Jignesh Patel, MD
Email	jignesh.patel@stonybrookmedicine.edu
Status	Recruiting
Phase	Early Phase 1
Start date	August 2016
Completion date	July 2022

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