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NCT02303548 Clinical Trial

Bicarbonate in Patients With Out-of-hospital Cardiac Arrest

Cardiac Arrest Clinical Trial

Official title:
Pilot Study of Bicarbonate Injection for Improving Outcome in Patients With Out-of-hospital Cardiac Arrest, Double-blind Randomized Control Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02303548
Other study ID # BicarbonateinCPR001
Secondary ID
Status Completed
Phase Phase 2
First received
Last updated
Start date October 2014
Est. completion date February 2016

Study information
Verified date February 2022
Source Asan Medical Center
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

A pilot study to evaluate the effect of sodium bicarbonate administration on cardiopulmonary resuscitation results and outcomes in cardiac arrest patient with severe metabolic acidosis.

Recruitment information / eligibility
Status Completed
Enrollment 50
Est. completion date February 2016
Est. primary completion date February 2016
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - adult cardiac arrest patient with arterial pH <7.1 or bicarbonate <10mmEq/L checked at 10 minutes of cardiopulmonary resuscitation Exclusion Criteria: - age <18 trauma patient Do Not Resuscitate state

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Sodium bicarbonate
Administer Sodium bicarbonate 50 mEq IV over 2 minutes
• Normal saline
Placebo

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Asan Medical Center

Outcome
Type Measure Description Time frame Safety issue
Primary Return of Spontaneous Circulation (ROSC) Percentage of Participants with Return of Spontaneous Circulation (ROSC) checked during CPR, duration of ROSC >20 min
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