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Clinical Trial Summary

The purpose of this clinical trial is to learn whether the study medicine (called lorlatinib) is safe and effective for the treatment of non-small cell lung cancer that is caused by an abnormal anaplastic lymphoma kinase (ALK) gene. This study is seeking participants whose lung cancer has progressed after receiving either alectinib or ceritinib as their first treatment. Participants will take part in this study for up to approximately 4 years, depending on when the study is completed and how their cancer responds to the study treatment. They will take lorlatinib orally (by mouth) once daily. Participants will visit the study site about every six weeks to meet with the study team. During these visits, the study team will monitor the safety and effects of lorlatinib.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04362072
Study type Interventional
Source Pfizer
Contact
Status Active, not recruiting
Phase Phase 4
Start date September 29, 2020
Completion date June 25, 2024

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