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Carcinoma, Renal Cell clinical trials

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NCT ID: NCT03592199 Active, not recruiting - Clinical trials for Clear Cell Renal Cell Carcinoma

Biomarker Study of Pts With Metastatic ccRCC Undergoing Sequential Therapy With 1st Line Sunitinib and 2nd Line Axitinib

SuAx
Start date: December 11, 2017
Phase: Phase 2
Study type: Interventional

This is a prospective single arm phase II study to evaluate potential prognostic and/or predictive biomarkers in patients with metastatic ccRCC undergoing treatment with 1st line sunitinib on a 4/2 schedule followed by axitinib on 2nd line therapy.

NCT ID: NCT03587662 Active, not recruiting - Clinical trials for Metastatic Renal Cell Carcinoma

Ixazomib, Gemcitabine, and Doxorubicin in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

Start date: August 17, 2018
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well ixazomib, gemcitabine, and doxorubicin work in treating patients with kidney cancer that has spread to other places in the body (locally advanced or metastatic). Ixazomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as gemcitabine and doxorubicin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ixazomib, gemcitabine, and doxorubicin may work better in treating patients with kidney cancer.

NCT ID: NCT03581773 Recruiting - Mucositis Clinical Trials

Folic Acid Supplement Versus Placebo for Treating Mucositis Adverse Events in Metastatic Renal Cell Carcinoma Patients Receiving Targeted Therapy

FASTERCC
Start date: December 20, 2017
Phase: Phase 2
Study type: Interventional

FASTERCC: Folic acid supplement versus placebo for treating mucositis adverse events in metastatic renal cell carcinoma patients receiving targeted therapy. A randomized, double-blind trial from the Danish renal cancer group (DARENCA study-4)

NCT ID: NCT03576131 Terminated - Colorectal Cancer Clinical Trials

GEN1029 (HexaBody®-DR5/DR5) Safety Trial in Patients With Malignant Solid Tumors

Start date: April 30, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the trial is to evaluate the safety of GEN1029 (HexaBody®-DR5/DR5) in a mixed population of patients with specified solid tumors

NCT ID: NCT03575611 Suspended - Clinical trials for Metastatic Renal Cell Carcinoma

Stereotactic Body Radiation Therapy in Treating Patients With Oligometastatic Renal Cell Carcinoma

Start date: June 14, 2018
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well stereotactic body radiation therapy works in treating patients with kidney cancer that has spread to other places in the body (metastatic). Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue.

NCT ID: NCT03568435 Completed - Kidney Cancer Clinical Trials

Safety and Effectiveness of Nivolumab in Recurring Kidney Cancer Participants

Start date: February 14, 2018
Phase:
Study type: Observational

A non-interventional, medical record review of clinical data collected from Japanese participants with recurring kidney cancer

NCT ID: NCT03562507 Terminated - Clinical trials for Renal Cell Carcinoma, Metastatic

Multi-center Trial of ESK981 in Combination With Nivolumab in Patients With Metastatic Renal Cell Carcinoma

ERICA
Start date: April 11, 2019
Phase: Phase 2
Study type: Interventional

The objective of the trial is to determine the clinical efficacy of ESK981 in combination with nivolumab therapy in patients with metastatic renal cell carcinoma (RCC).

NCT ID: NCT03556943 Completed - Clinical trials for Renal Cell Carcinoma

Using Virtual Reality (VR) Models for Preoperative Planning - Mayo Clinic

Start date: May 15, 2018
Phase: N/A
Study type: Interventional

A prospective, randomized, controlled study designed to assess whether digital virtual reality (VR) models, created from existing CT scans and MRIs, provide surgeons with an improved understanding of their patients' anatomy, resulting in more efficient operations (robotic partial nephrectomy) and improved patient care.

NCT ID: NCT03556046 Completed - Clinical trials for Clear Cell Renal Carcinoma

89Zr-girentuximab ) Dosimetry in CCRC Study - ZIR-DOSE

Start date: April 5, 2018
Phase: Phase 1
Study type: Interventional

The study is designed to explore the safety and tolerability as well as diagnostic 89Zr-girentuximab for imaging CCRC by PET/CT. This study does not offer any treatment for patients with CCRC; therefore, patients will be offered state of the art therapeutic options after imaging with the study drug 89Zr-girentuximab. Cancer treatment will not be delayed by study participation.

NCT ID: NCT03554434 No longer available - Breast Cancer Clinical Trials

An Expanded Access Program for AM0010 (Pegilodecakin)

Start date: n/a
Phase:
Study type: Expanded Access

This is an Expanded Access Program (EAP) available to patients who have advanced cancers, who have failed or progressed on standard of care systemic therapy and do not qualify for ongoing clinical trials.