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Carcinoma, Non-Small-Cell Lung clinical trials

View clinical trials related to Carcinoma, Non-Small-Cell Lung.

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NCT ID: NCT02409342 Completed - Clinical trials for Non-Squamous Non-Small Cell Lung Cancer, Squamous Non-Small Cell Lung Cancer

A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]

Start date: July 20, 2015
Phase: Phase 3
Study type: Interventional

This randomized, open-label study will evaluate the efficacy and safety of atezolizumab compared with chemotherapy consisting of a platinum agent (cisplatin or carboplatin per investigator discretion) combined with either pemetrexed (non-squamous disease) or gemcitabine (squamous disease) in programmed death-ligand 1 (PD-L1)-selected, chemotherapy-naive participants with Stage IV Non-Squamous or Squamous NSCLC.

NCT ID: NCT02409108 Completed - Solid Tumor, Adult Clinical Trials

Perfusion-Induced Hyperthermia for Metastatic Carcinoma

Start date: July 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to gather information on how safe the hyperthermia treatment delivered via the Exatherm-TBH (the device that will heat your blood and deliver it back to you), added to the best supportive care is to patients who have advanced persistent or recurrent, unresectable Cancer.

NCT ID: NCT02407327 Completed - Clinical trials for Advanced Non Small Cell Lung Cancer

Individualized Treatment of Patients With Advanced NSCLC: Potential Application for Circulating Tumor Cells (CTC) Molecular and Phenotypical Profiling

2012/52
Start date: December 1, 2012
Phase:
Study type: Observational

The purpose of this study is to determine the percentage of CTC-positive patients and total CTC numbers in patients with advanced Non Small Cell Lung Cancer .

NCT ID: NCT02403271 Completed - Breast Cancer Clinical Trials

A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors

Start date: March 2015
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Phase 1b/2, multi-center study to assess the safety and efficacy of ibrutinib in combination with durvalumab (MEDI4736) in participants with relapsed or refractory solid tumors.

NCT ID: NCT02403193 Completed - Clinical trials for Non-small Cell Lung Cancer (NSCLC)

Trial of PBF-509 and PDR001 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

AdenONCO
Start date: October 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety, tolerability, feasibility and preliminary efficacy of the administration of PBF-509 (Adenosine A2a receptor antagonist) as single agent or in combination with PDR001 (programmed cell death 1 receptor antibody (PD-1 Ab)) to NSCLC patients.

NCT ID: NCT02395172 Completed - Clinical trials for Carcinoma, Non-Small-Cell Lung

Avelumab in Non-Small Cell Lung Cancer (JAVELIN Lung 200)

Start date: March 24, 2015
Phase: Phase 3
Study type: Interventional

The main purpose of this study was to demonstrate superiority with regard to overall survival of avelumab versus docetaxel in participants with programmed death ligand 1 (PD-L1) positive, non-small cell lung cancer (NSCLC) after failure of a platinum-based doublet.

NCT ID: NCT02394548 Completed - Clinical trials for Small Cell Lung Carcinoma

Phase I Trial Of IMRT Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Lung Cancer

Start date: June 2015
Phase: N/A
Study type: Interventional

This research study is examining the benefit of a novel radiation planning approach on the likelihood of developing severe esophagitis (irritation and inflammation of the esophagus) during the course of radiation therapy with concurrent chemotherapy which is associated with very painful and difficult swallowing.

NCT ID: NCT02392507 Completed - Clinical trials for Carcinoma, Non-Small Cell Lung Cancer (NSCLC)

A Study of Nab-Paclitaxel and Carboplatin Plus Necitumumab (LY3012211) in Participants With Stage IV Squamous NSCLC

Start date: October 12, 2015
Phase: Phase 2
Study type: Interventional

The purpose of the study is to determine if nab-paclitaxel and carboplatin chemotherapy plus necitumumab is effective and safe in participants with stage IV squamous non-small cell lung cancer.

NCT ID: NCT02388919 Completed - Clinical trials for Non-small Cell Lung Cancer

Study of Anlotinib in Patients With Advanced Non-small Cell Lung Cancer(ALTER0303)

ALTER0303
Start date: February 26, 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Evaluate the efficacy and safety of Anlotinib as the 3-line treatment of patients with advanced non-small lung cancer, with placebo control.

NCT ID: NCT02387307 Completed - Melanoma Clinical Trials

A Study of rSIFN-co in Subjects With Advanced Solid Tumors

rSIFN-01
Start date: July 2013
Phase: Phase 1
Study type: Interventional

This is a multicenter, open-label, phase I study of rSIFN-co (3 times a week via subcutaneous injection for 21 days, with 1 week of washout per cycle).