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Carcinoma, Non-Small-Cell Lung clinical trials

View clinical trials related to Carcinoma, Non-Small-Cell Lung.

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NCT ID: NCT03429192 Completed - Clinical trials for Non-small Cell Lung Cancer

A Study to Explore Clinical Characteristics and Prognoses of N2 Patients With Non-small Cell Lung Cancer

Start date: December 1, 2017
Phase:
Study type: Observational

A study to compare patient survivals in the N2 patients with non-small cell lung cancer in the subgroups of lymph skip metastases and non-skip metastases

NCT ID: NCT03427567 Completed - Clinical trials for Non-small Cell Lung Cancer

A Study to Evaluate Effectiveness of Sublobar Dissection in Patients With Non-small Cell Lung Cancer

Start date: December 1, 2017
Phase:
Study type: Observational

A study to evaluate effectiveness of sublobar dissection in patients with non-small cell lung cancer

NCT ID: NCT03415126 Completed - Cancer Clinical Trials

A Study of ASN007 in Patients With Advanced Solid Tumors

Start date: January 19, 2018
Phase: Phase 1
Study type: Interventional

The study is divided into two parts. The first part of the study will test various doses of ASN007 to find out the highest safe dose to test in five specific groups. The second part of the study will test how well ASN007 can control cancer.

NCT ID: NCT03414814 Completed - Clinical trials for Locally Advanced or Metastatic NSCLC

Osimertinib for NSCLC With EGFR Exon 20 Insertion Mutation

Start date: January 4, 2018
Phase: Phase 2
Study type: Interventional

This is a single-arm, non-randomized multicentre phase 2 study in NSCLC patients with EGFR exon 20 insertion mutation, whose disease has progressed on standard chemotherapy.

NCT ID: NCT03413956 Completed - Clinical trials for Non Small Cell Lung Cancer

An Observational Study to Explore Clinical Characteristics of the Patients With T1 Non-small Cell Lung Cancer

Start date: December 1, 2017
Phase:
Study type: Observational

The real-world observational study was designed to explore the odd factors of lymph metastases in the patients with T1 non-small cell lung cancer, the effects of clinical characteristics on lymph metastases, and compare the differences in lymph metastases in the subgroups.

NCT ID: NCT03410108 Completed - Clinical trials for ALK-positive Advanced NSCLC

Phase 2 Study of Brigatinib in Japanese Participants With Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer (NSCLC)

Start date: January 29, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate efficacy and safety of brigatinib in Japanese participants with anaplastic lymphoma kinase (ALK)-positive NSCLC.

NCT ID: NCT03409458 Completed - Clinical trials for Non-Small Cell Lung Cancer (NSCLC)

A Dose Escalation and Confirmation Study of PT-112 in Advanced Solid Tumors in Combination With Avelumab

PAVE-1
Start date: April 24, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Phase 1/2, open-label, multi-center, non-randomized, dose-escalation study of PT-112 in combination with the anti-PD-L1 antibody, avelumab, in selected advanced solid tumors. The study is to be conducted in two parts: the Dose Escalation Phase of PT-112 within the combination and the Dose Confirmation Phase in patients with non-small cell lung cancer who will be treated at the RP2D.

NCT ID: NCT03406468 Completed - Clinical trials for Non-Small Cell Carcinoma of Lung, TNM Stage 4

Re-Induction After Initial Response With Immune Therapy With Radiotherapy in Lung Cancer

Start date: July 15, 2019
Phase: Phase 2
Study type: Interventional

Radiotherapy in combination with different forms of immune therapy improved consistently local tumor control and very interestingly, lead to better systemic tumor control and the induction of specific anti-cancer immunity with a memory effect. In small series, it has been shown that a new long-lasting remission can be induced by irradiating one tumor site in patients who showed cancer progression after an initial response to immune therapy. In these series, the original immune therapy was continued and the treatment was very well tolerated. In this study the progression-free survival after radiotherapy to a single lesion will be investigated in patients with stage IV non-small cell lung cancer (NSCLC), who have at least achieved stable disease with immune therapy alone or concurrent immune therapy and chemotherapy.

NCT ID: NCT03403127 Completed - Lung Cancer Clinical Trials

PET CT Re-Planning NSCLC (4DCT-PET)

Start date: May 20, 2008
Phase: N/A
Study type: Interventional

This study will see whether the addition of more frequent planning CTs during the course of radiation, and of Positron Emission Tomography (PET), a diagnostic test similar to CT, prior to and during a course of radiation may provide information that could potentially be used during the treatment to improve the initial radiation plan.

NCT ID: NCT03394118 Completed - NSCLC Clinical Trials

TAGRISSO (Osimertinib) in NSCLC Patients in Whom T790 Mutations Are Detected by Liquid Biopsy

Start date: August 11, 2017
Phase: Phase 2
Study type: Interventional

In this trial, anti-tumor efficacy of TAGRISSO in NSCLC patients in whom T790 mutations are detected by liquid biopsy.