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Carcinoma, Hepatocellular clinical trials

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NCT ID: NCT03192618 Recruiting - Clinical trials for Hepatocellular Carcinoma

The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma And Microvascular Invasion (MVI) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.

Start date: July 1, 2017
Phase: Phase 3
Study type: Interventional

To compare The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma And Microvascular Invasion (MVI) After Hepatectomy.

NCT ID: NCT03191123 Recruiting - Clinical trials for Carcinoma, Hepatocellular

Resection Versus Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma With Solitary Huge Tumor

Start date: July 5, 2016
Phase: N/A
Study type: Interventional

This clinical trial aims to compare hepatectomy with Transarterial Chemoembolization (TACE) for Hepatic Cellular Cancer With Solitary Huge Tumor (≥5cm). All patients will be divided into two group.One group will receive hepatic resection, while an another equivalent group patients will be treated with Transarterial Chemoembolization.

NCT ID: NCT03189992 Recruiting - Clinical trials for Malignant Tumor of Small Intestine Metastatic to Liver

Study of TCM Syndrome of Hepatocellular Carcinoma and Colorectal Cancer Based on System Science

Start date: January 2014
Phase: Phase 1
Study type: Interventional

Traditional Chinese medicine (TCM) syndrome is a core foundation of disease knowledge, clinical diagnosis and treatment and curative effect evaluation in TCM. "Same TCM Syndrome for Different Diseases" and "Same Treatment for Different Diseases" is one of the characteristics of TCM syndrome differentiation and treatment. This study is the "TCM disease syndrome combination" research baced on principles and methods of system biology, which is through acquisition of primary hepatocellular carcinoma (HCC) and colorectal cancer patients with TCM syndrome information, detection of clinical indicators and genomic, proteomic, and metabolites changes, analyzing the correlation between TCM syndromes and biological information, and revealing its biological material characteristics and the molecular mechanisms of "Same TCM Syndrome for Different Diseases";Developing and implementing the program of TCM syndrome differentiation and treatment for HCC and colorectal cancer to evaluate the efficacy of TCM syndrome based-treatment of HCC and colorectal cancer with TCM syndrom scores, clinical and systems biological indicators, quality of life and survival rate, and to revealing the mechanism of the "Same Treatment for Different Diseases".

NCT ID: NCT03186898 Recruiting - Clinical trials for Unrectable or Locally Recurrent Hepatocellular Carcinoma

Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

Start date: June 22, 2017
Phase: Phase 3
Study type: Interventional

This phase III trial studies how well radiation therapy with protons works compared with photons in treating patients with liver cancer. Radiation therapy, such as photon therapy, uses high energy x-rays to send the radiation inside the body to the tumor while proton therapy uses a beam of proton particles. Proton therapy can stop shortly after penetrating through the tumor and may cause less damage to the surrounding healthy organs and result in better survival in patients with liver cancer.

NCT ID: NCT03184493 Recruiting - Liver Cancer Clinical Trials

Celebrex and Metformin for Postoperative Hepatocellular Carcinoma

XBD
Start date: June 2, 2017
Phase: Phase 3
Study type: Interventional

This prospective trial aims to compare the role of celebrex alone, metformin alone, and celebrex plus metformin in preventing HCC recurrence after hepatic resection.

NCT ID: NCT03178929 Not yet recruiting - Clinical trials for Primary Liver Cancer

Effect of SAMe Treatment on Recurrence After Radical Treatment of Primary Hepatic Carcinoma

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to explore the effect of SAMe on recurrence after radical treatment of Primary liver cancer.

NCT ID: NCT03178409 Completed - Clinical trials for Hepatocellular Carcinoma

Combined HCC-MFCCC

Start date: January 1, 2004
Phase: N/A
Study type: Observational

Combined hepatocellular and mass-forming cholangiocarcinoma (cHCC-MFCCC) is a rare tumor. The aim of this study was the analysis of the outcome comparing such tumor with classic hepatocellular carcinoma (HCC) and mass-forming cholangiocarcinoma (MFCCC).

NCT ID: NCT03176485 Completed - Clinical trials for Hepatocellular Carcinoma

Evaluation of Pathway Modulation by Raf, MEK, & Kinase Inhibitors

Start date: October 17, 2014
Phase: N/A
Study type: Interventional

This is a pilot study designed to evaluate the cutaneous effect of systemic inhibition of the tyrosine kinase pathway in the presence or absence of solar simulated light exposure. A maximum of 45 subjects will be accrued into the overall study we anticipate approximately 25 patients in the Raf inhibitor group and 10 patients each into the Tyrosine Kinase and MEK inhibitor arms of the study.

NCT ID: NCT03175705 Recruiting - Clinical trials for Hepatocellular Carcinoma

Adoptive Transfer of Specific HCC Antigens CD8+ T Cells for Treating Patients With Relapsed/Advanced HCC

Start date: May 1, 2017
Phase: Phase 1
Study type: Interventional

This study enrolls patients who have relapsed/advanced hepatocellular carcinoma (HCC, BCLC stage C). The HCC tumor relapsed or metastasized through the body after standard treatment or the patients cannot receive standard treatment under current conditions. This research study uses specific HCC antigens CD8+ T cells, a new experimental treatment. The purpose of this study is to evaluate the safety and tolerance as well as the potential clinical efficacy of an adoptive transfer of CD8+ T cells, sorted with human leukocyte antigen (HLA)-peptide multimers and specific for Glypican (GPC)-3 /New York Esophageal Squamous-1 (NY-ESO-1) /alpha-fetoprotein (AFP) antigens and cultured in vitro, to patients suffering from relapsed/advanced hepatocellular carcinoma (HCC).