Medical Treatment of Solid Tumors at the Lyon University Hospital Cancer Institute During the First Wave of COVID-19 in France: A Conservative Approach

Cancer Clinical Trial

— COCA  

Official title:

Medical Treatment of Solid Tumors at the Lyon University Hospital Cancer Institute During the First Wave of COVID-19 in France: A Conservative Approach

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04910633
• Other study ID #: 69HCL21_0005
• Status: Completed
• Start date: December 2, 2020
• Est. completion date: January 22, 2021

Study information

• Verified date: May 2021
• Source: Hospices Civils de Lyon
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

An article to present how cancer patients were taken in charge at Lyon University Hospital Cancer Institute (France) during the first peak of the COVID-19 pandemic between March and May 2020 is under writing.

It will present strategies that were set-up to avoid cross-contamination between patients and caregivers, patients treatment adaptation (timing, dosage,..) and how consultations, multidisciplinary team meetings, surgical procedures and clinical trials were impacted.

Part of this article will also illustrate the characteristics of patients with a solid tumor(s) that have been hospitalized during this timeframe for the COVID-19. How cancer type and stage affect Covid severity and mortality.will be described for a small sample of patients (44). These qualitative figures will be compared to literature current state of the art.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 44
• Est. completion date: January 22, 2021
• Est. primary completion date: December 9, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients with a LUHCI code created after 2015 and a LUHCI COVID-19 code created between March 2020 and May 2020.

Exclusion Criteria:

• Patients who did not allow the reuse of their medical file data for research related to COVID-19-

Related Conditions & MeSH terms

• Cancer
• Covid19
• Neoplasms
• Solid Tumor

Intervention

Other:
• COCA is an observational study based on retrospective data issued from patient medial file.
The following parameters will be collected from the medical files of the patients involved in this study: Age Gender Cancer type Cancer Stage Cancer Treatment COVID-19 severity (based on chest X-Ray damage. Low =25%, Middle: between 25-50%, High above 50%) Living Status Attribution of Mortality to COVID status Comorbidities

Locations

Country	Name	City	State
France	Lyon University Hospital Cancer Institute	Bron

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Illustration of the repartition of COVID+ patient severity (Low/Medium/Severe status) depending on cancer nature, stage and patient age.	COVID-19 severity will be determined based on chest X-Ray damage as follow. Low severity : =25% of chest X-Ray damage, Middle severity: between 25-50% of chest X-Ray damage, High Severity : above 50% of chest X-Ray damage.; A graphic will then be drafted to present the relationship between Covid-19 severity depending on patient age, cancer nature, and cancer stage.	At the end of Month 1