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Pancytopenia Related to PARP Inhibitors (PancytoRIB)

Cancer Clinical Trial

Official title:
Pancytopenia Related to PARP Inhibitors in Cancer Patients : an Observational and Retrospective Study Using the WHO's Pharmacovigilance Database (PancytoRIB)

Clinical Trial Summary

Although PARP inhibitors (PARPi) have proved effective in treating many cancers, few patients receiving PARPi may experience rare but serious adverse events such as pancytopenia. Today, data about pancytopenia are scarce. The objective was to investigate reports of pancytopenia adverse events related to PARPi, including olaparib, rucaparib, niraparib, talazoparib, veliparib and pamiparib using the World Health Organization's (WHO) pharmacovigilance database: VigiBase.

Clinical Trial Description

Here, investigators use the World Health Organization's (WHO) database of individual safety case reports, to identify cases of pancytopenia related to PARPi. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04774627
Study type Observational
Source University Hospital, Caen
Contact
Status Completed
Phase
Start date February 7, 2021
Completion date March 24, 2021
View Details
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