Characterization of Cancer Tissue Using 3D Biosynthetic Material

Cancer Clinical Trial

Official title:

Characterization of Cancer Tissue Using 3D Biosynthetic Material

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02678078
• Other study ID #: 0671-15-RMB
• Status: Recruiting
• Phase: N/A
• First received: February 4, 2016
• Last updated: May 5, 2016
• Start date: February 2016
• Est. completion date: January 2018

Study information

• Verified date: May 2016
• Source: Technion, Israel Institute of Technology
• Contact: tarek Saadi, Dr.
• Phone: 97247772947
• Email: t_saadi[@]rambam.health.gov.il
• Is FDA regulated: No
• Health authority: Israel: Ministry of Health
• Study type: Observational

Clinical Trial Summary

Characterization of Cancer Tissue Using 3D Biosynthetic Materials. Using liver biopsy from stage 4 cancer patients, the investigators will evaluate and characterize the metastatic cells.

Description:

The investigators' biomaterial lab has developed an in vitro diagnostic system in which a cancer tumor is placed inside a 3D hydrogel. This material has similar properties to the human tissue and can visualize cell migration and proliferation. In this system, the investigators have already characterised human metastatic cells obtained from nude mice tumors. The diagnostic assay is able to evaluate the reduction in cell growth associated with anti-cancer drug therapy. The next step is to test the in vitro diagnostic system using human tissue samples from human patients, and to validate the system as a simple and effective a priori diagnostic tool for characterizing patient tumours.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: January 2018
• Est. primary completion date: January 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• liver tumor

Exclusion Criteria:

• refuse to volunteer

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Cancer

Intervention

Procedure:
• Analyzing biopsy samples
Analyzing biopsy samples that is preformed as part of the patient treatment.

Locations

Country	Name	City	State
Israel	Rambam	Haifa

Sponsors (2)

Lead Sponsor	Collaborator
Technion, Israel Institute of Technology	Rambam Health Care Campus

Country where clinical trial is conducted

Israel, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	cell growth	biopsy will be placed inside 3D gel, and growth will be measured over 1 week time.	1 week	No