Advanced MRI Sequences for Radiation Therapy Treatment Planning

Cancer Clinical Trial

Official title:

Investigation on the Utility of Advanced MRI Imaging Methods for Radiation Therapy Treatment Planning

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02340715
• Other study ID #: Advanced MRI
• Status: Completed
• Phase: N/A
• First received: September 10, 2014
• Last updated: October 30, 2017
• Start date: February 2009
• Est. completion date: June 2015

Study information

• Verified date: October 2017
• Source: Medical College of Wisconsin
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to determine if it would be helpful to use advanced MRI imaging techniques to take additional views of the tumor target for radiation treatment planning or treatment follow-up MRI.

Description:

The results of this research project will be used to establish a standard MRI protocol specific to each tumor or disease site. An MRI protocol is a list of MR image types that are acquired for each disease site. These images are used to generate the patient's treatment plan.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 158
• Est. completion date: June 2015
• Est. primary completion date: June 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 89 Years

Eligibility

Inclusion Criteria:

• Patients aged 18 years older of any race or gender with anal canal, brain, breast, cervix, esophagus, gynecology, head and neck, lung, pancreas, primary liver or liver metastases, prostate cancer or sarcoma either undergoing MRI scan for radiation treatment planning or a post treatment MRI

• Voluntarily signs an IRB approved consent form

Exclusion Criteria:

• Inability to obtain informed consent from the patient or their medical power of attorney

• Patients who are not undergoing MR for radiation treatment planning

• Patients who will not have MRI scans after treatment

• Patients with pacemakers or other non-MRI compatible metallic implants

• Pregnant women, by self report using a standard MRI questionnaire

• Patients who will not receive contrast agent as part of their standard MR, will participate only in the non-contrast portion of the study

Related Conditions & MeSH terms

• Cancer

Locations

Country	Name	City	State
United States	Froedtert Hospital	Milwaukee	Wisconsin

Sponsors (1)

Lead Sponsor	Collaborator
Medical College of Wisconsin

Country where clinical trial is conducted

United States, 

References & Publications (1)

Khoo VS, Dearnaley DP, Finnigan DJ, Padhani A, Tanner SF, Leach MO. Magnetic resonance imaging (MRI): considerations and applications in radiotherapy treatment planning. Radiother Oncol. 1997 Jan;42(1):1-15. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of Participants Successfully Contributing MRI Data	We tested these Advanced MR protocols to evaluate which ones would best visualize the target region. This helped us determine the optimum MR SIM protocols for different sites that became clinical standard.	up to 4 weeks from imaging