Cancer of Breast Clinical Trial
Official title:
Randomized Study on Postmenopausal Women With Early Stage Breast Cancer: Adjuvant Hypofractionated Whole Breast Irradiation (WBI) Versus Accelerated Partial Breast Irradiation (APBI)
Selected patients with early stage breast cancer undergone conservative surgery were randomized in two arms: Hypofractionated Whole Breast Irradiation versus Accelerated Partial Breast Irradiation.
Patients treated with Hypofractionated Whole Breast Irradiation (WBI) received SIB
irradiation of the whole breast and surgical bed at two different dose levels. Dose
prescription was 40.5 Gy to PTVWB and 48.0 Gy to PTVboost in 15 fractions over 3 weeks, with
simultaneous integrated boost delivering 2.7 and 3.2Gy/fraction for each PTV respectively.
Daily image guided radiotherapy (IGRT) were generated before each treatment session in each
patient to verify the set-up.
Accelerated Partial Breast Irradiation (APBI) using external intensity -modulated
radiotherapy (VMAT RA) was delivered at a dose of 30 Gy in five 6-Gy/day fractions over 10
days (every other day) with IGRT at each treatment.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Withdrawn |
NCT03285607 -
MCS110 Combined With Neoadjuvant Doxorubicin, Cyclophosphamide, and Weekly Paclitaxel in Patients With Hormone-Receptor Positive and HER2- Breast Cancer
|
Phase 1 | |
Completed |
NCT02225470 -
Eribulin Versus Vinorelbine in Subjects With Locally Recurrent or Metastatic Breast Cancer Previously Treated With Anthracyclines and Taxanes
|
Phase 3 | |
Withdrawn |
NCT05191004 -
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC
|
Phase 1/Phase 2 | |
Completed |
NCT01271738 -
Evaluating and Comparing Two Surgical Methods for Treatment of Early Stage Breast Cancer
|
N/A | |
Terminated |
NCT02669914 -
MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived Tumors
|
Phase 2 | |
Completed |
NCT01980823 -
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer
|
Early Phase 1 | |
Completed |
NCT02658708 -
Bright Light on Fatigue in Women Being Treated for Breast Cancer
|
Phase 1 | |
Completed |
NCT02891681 -
Ultrasound and Near Infrared Imaging for Predicting and Monitoring Neoadjuvant Treatment
|
N/A | |
Completed |
NCT05584644 -
A Study to Describe the Breast Cancer Patient Population, Treatment, and Results in Indian Patients Receiving Combinations of the Medicines Called Palbociclib for Advanced Breast Cancer
|
||
Recruiting |
NCT05252390 -
NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors
|
Phase 1/Phase 2 | |
Completed |
NCT03084536 -
PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery
|
Phase 2 | |
Terminated |
NCT02907918 -
Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer
|
Phase 2 | |
Completed |
NCT03007979 -
Alternative Dosing Schedule of Palbociclib in Metastatic Hormone Receptor Positive Breast Cancer
|
Phase 2 | |
Terminated |
NCT02462200 -
Shave Margins in Breast Conservation Therapy
|
Phase 2 | |
Completed |
NCT03592121 -
Study to Investigate the Effect of AB-101 in Breast Cancer Survivors
|
Early Phase 1 | |
Terminated |
NCT02642094 -
Aging Mammary Stem Cells and Breast Cancer Prevention
|
Phase 2 | |
Active, not recruiting |
NCT04855552 -
Telehealth Weight Loss Program for Breast Cancer Survivors
|
N/A | |
Active, not recruiting |
NCT05364450 -
Facilitating Adaptive Coping With Fear of Recurrence Among Breast Cancer Survivors
|
N/A | |
Completed |
NCT03494400 -
Aerobic Training in Treatment for Breast Cancer
|
N/A | |
Recruiting |
NCT02476786 -
Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
|
Phase 2 |