Calorie Restriction Clinical Trial
Official title:
Legacy Effects of CALERIE™, a 2-year Calorie Restriction Intervention, on Hallmarks of Healthspan and Aging
The purpose of the CALERIE Legacy Study is to follow up on the health and wellness of participants from phase 2 of the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) trial, which was conducted from 2007 to 2011.
The CALERIE Legacy Study is an observational follow-up study of participants from phase 2 the CALERIE trial, the first randomized controlled trial of calorie restriction (CR) in humans without obesity. The overarching goal of the CALERIE Legacy Study is to examine whether two years of CR results in sustained improvements in the biological, phenotypic, and functional hallmarks of human aging 10 to 15 years after the structured intervention. Participants will complete clinical assessments, dietary recalls, and questionnaires, and laboratory evaluations will be performed on blood and urine samples. The study also includes an optional biospecimen banking component. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03745612 -
Time Restricted Feeding on Weight Loss and Cardio-protection (TREATY Trial)
|
N/A | |
| Completed |
NCT01243879 -
The Effect of Food Stimuli on the Calorie Restriction Response in Healthy Subjects
|
N/A |