Cachexia Clinical Trial
Official title:
Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients
NCT number | NCT01015274 |
Other study ID # | 09-150 |
Secondary ID | 1R43AR054993-01A |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | October 2009 |
Verified date | July 2011 |
Source | The University of Texas Medical Branch, Galveston |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The long-term objective of this research is to develop a non-invasive approach for early assessment of which patients are at high risk for future development of skeletal muscle atrophy. The investigators hypothesize that the rate constant for the terminal portion of the isotope decay curve following ingestion of a single oral dose of deuterated-3-methylhistidine (D-3MH) provides an accurate measure of this increased risk and that this rate constant can be measured non-invasively from timed spot urine samples.
Status | Completed |
Enrollment | 10 |
Est. completion date | |
Est. primary completion date | |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 30 Years to 75 Years |
Eligibility |
Inclusion Criteria: - Male - 30-75 years old - Body Mass Index (BMI) <27 kg/m2 Exclusion Criteria: - Uncontrolled hypertension - Glomerular filtration rate less than 60 mL/min/1.73 m2 - History of recurrent gastrointestinal bleeding - Unable or unwilling to provide informed consent - Ongoing anti-coagulant therapy |
Country | Name | City | State |
---|---|---|---|
United States | University of Texas Medical Branch | Galveston | Texas |
Lead Sponsor | Collaborator |
---|---|
The University of Texas Medical Branch, Galveston |
United States,
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