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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01015274
Other study ID # 09-150
Secondary ID 1R43AR054993-01A
Status Completed
Phase
First received
Last updated
Start date October 2009

Study information

Verified date July 2011
Source The University of Texas Medical Branch, Galveston
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The long-term objective of this research is to develop a non-invasive approach for early assessment of which patients are at high risk for future development of skeletal muscle atrophy. The investigators hypothesize that the rate constant for the terminal portion of the isotope decay curve following ingestion of a single oral dose of deuterated-3-methylhistidine (D-3MH) provides an accurate measure of this increased risk and that this rate constant can be measured non-invasively from timed spot urine samples.


Recruitment information / eligibility

Status Completed
Enrollment 10
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 30 Years to 75 Years
Eligibility Inclusion Criteria:

- Male

- 30-75 years old

- Body Mass Index (BMI) <27 kg/m2

Exclusion Criteria:

- Uncontrolled hypertension

- Glomerular filtration rate less than 60 mL/min/1.73 m2

- History of recurrent gastrointestinal bleeding

- Unable or unwilling to provide informed consent

- Ongoing anti-coagulant therapy

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
United States University of Texas Medical Branch Galveston Texas

Sponsors (1)

Lead Sponsor Collaborator
The University of Texas Medical Branch, Galveston

Country where clinical trial is conducted

United States, 

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