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Burns clinical trials

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NCT ID: NCT03237442 Not yet recruiting - Ocular Corneal Burn Clinical Trials

Umbilical Cord Mesenchymal Stem Cells Injection for Ocular Corneal Burn

Start date: January 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Ocular chemical burn is one of the causes of vision loss in China, and there are no satisfactory treatment. Human umbilical cord mesenchymal stem cells(UC-MSCs) have the biological characteristics of self-renewal, immune regulation, multidirectional differentiation and tissue repair. Our preliminary research showed that in corneal alkali injury rabbits, the UC-MSCs can accelerated the cornea repair, inhibited angiogenesis. The aim of this study is to access the efficacy and safety of UC-MSCs in the treatment of corneal burn in human.

NCT ID: NCT03229564 Recruiting - Burns Clinical Trials

Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Children

Start date: October 25, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in children with partial deep dermal and full thickness burns.

NCT ID: NCT03227146 Active, not recruiting - Burns Clinical Trials

Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents

Start date: October 25, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in adults and adolescents with partial deep dermal and full thickness burns.

NCT ID: NCT03217526 Completed - Burns Clinical Trials

Gait Training in Patients With Burn Injury

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Twenty-four individuals with burn injury will be included in this study. Participants with burn injury will evaluate with the following assessment tools: Demographic datas; age, gender, height, body mass index; burn caharacteristics; type of burn injury, degree of burn injury, localization of burn injury and total burn surface area will be recorded. Gait parameters (step length, stride length, base support, step time, cycle time, cadence, velocity, single support, double support, swing ( % of gait cycle) and stance (% of gait cycle). will be recorded via GAITRite system.

NCT ID: NCT03205839 Completed - Burns Clinical Trials

Acceptance-based Self-help for Individuals With Visible Difference and Social Anxiety

Start date: July 27, 2017
Phase: N/A
Study type: Interventional

The acceptance and commitment therapy (ACT) model theoretically fits with treating appearance-related anxiety in individuals with a visible difference. This study examines the effectiveness of an acceptance-based self-help manual for this population.

NCT ID: NCT03204669 Completed - Critical Illness Clinical Trials

Trace Element Repletion Following Severe Burn Injury

Start date: June 1, 1999
Phase: N/A
Study type: Observational

Major burn patients are characterized by large exudative losses of Cu, Se and Zn. Trace element (TE) repletion has been shown to improve clinical outcome. The study aimed to check if our repletion protocols were achieving normalization of TE plasma concentrations of major burn patients and if the necessity for continuous renal replacement therapy (CRRT) might increase the needs.

NCT ID: NCT03197649 Completed - Burn Scar Clinical Trials

CO2 Laser Phototherapy for Management of Mature Burn Scars

Start date: May 22, 2017
Phase: N/A
Study type: Interventional

Evaluate mature burn scars before and after treatment with CO2 for patients age 3-21 while comparing the treated areas to an untreated control area in the same patient.

NCT ID: NCT03188913 Not yet recruiting - Burns Clinical Trials

Factor XIII in Major Burns Coagulation

Start date: June 19, 2017
Phase: N/A
Study type: Observational

Prospective observational study in which FXIII levels and coagulation tests and cicatrization are measured during the 30 days after the thermal trauma.

NCT ID: NCT03165331 Enrolling by invitation - Burns Clinical Trials

Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study

UNGFaceIT
Start date: April 1, 2016
Phase: N/A
Study type: Interventional

A visible difference can have a profound impact in a society with a massive emphasis on appearance and "looks". A vulnerable group is adolescents with a condition affecting their appearance as a result of injuries (burns, accidents), treatment (cancer), skin conditions or congenital anomalies (birthmarks, craniofacial conditions). Research has identified potential psychological difficulties, which, if not addressed, can lead to anxiety, depression, and eating disorders. In addition to medical treatment options, aiming at diminishing a difference that may be visible to others, young people with appearance concerns also need self-management skills. However, evidence-based interventions are scarce and specialised psychological treatment is difficult to reach. The Centre for Appearance Research (Bristol, UK) has developed an online intervention for adolescents, now translated into Norwegian (www.ungfaceit.no). UNG Face IT provides easy access to specialist advice and support via a home computer, using information, videos, and interactive activities. It provides advice, teaches coping and social skills, strengthening psychological adjustment to a visible difference. A systematic evaluation of the Norwegian version is needed. UNG Face IT could potentially address unmet needs, provide a cost-effective tool to reduce the need for "face-to-face" psychological and surgical/medical services, and contribute to make online health care available for young people with a visible difference.

NCT ID: NCT03162367 Completed - Burn Clinical Trials

Efficacy Of Autologous Epidermal Cell Suspension And Silver Sulfadiazine Ointment In Burn

Start date: April 10, 2019
Phase: Phase 2
Study type: Interventional

Different medical treatments are available for treatment of skin burns such as skin grafts and silver sulfadiazine ointment. These treatments are used for second degree burn as routine technique in burns units. Cell therapy is a new approach for treatment of skin disease.In this study we use autologous epidermal cell suspension to achieve better cosmetic and functional results in treatment of second degree burn.