Impact of Alpha Lipoic Acid Efficacy in Burning Mouth Syndrome

Status Recruiting

Clinical Trial Summary

A double-blind placebo-controlled trial is conducted in order to evaluate the efficacy of alpha lipoic acid (ALA) and determine the statistical significance of the outcome variables. Burning mouth syndrome (BMS) is defined as an oral burning sensation in the absence of clinical signs which could justify the syndrome. Recent studies suggest the existence of neurological factors as a possible cause of the disease.

Clinical Trial Description

A double-blind placebo-controlled trial is conducted in order to evaluate the efficacy of alpha lipoic acid (ALA) and determine the statistical significance of the outcome variables. 60 patients with BMS, in two groups: case group with 600 mg/day and placebo as control group; with a follow-up of 2 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05729529
Study type	Interventional
Source	University of Catania
Contact	Gaetano Isola
Phone	0953785652
Email	gaetano.isola@unict.it
Status	Recruiting
Phase	N/A
Start date	January 20, 2020
Completion date	May 30, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04475614` - Therapeutic Options for Treatment of Burning Mouth Syndrome	N/A
Completed	`NCT00374673` - Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders	Phase 3
Completed	`NCT02964728` - Botulinum Toxin in Burning Mouth Syndrome	Phase 2
Completed	`NCT04535973` - Hormonal Status and Quality of Life in Female Postmenopausal Patients With Burning Mouth Syndrome
Recruiting	`NCT06040190` - Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome	Phase 4
Not yet recruiting	`NCT05059418` - Burning Mouth Syndrome - New Diagnostic Criteria and Treatment	N/A
Recruiting	`NCT01867151` - Effect of Gluten Free Diet in Patients With Burning Mouth Syndrome	N/A
Completed	`NCT05872789` - Impact of Diazepam 1% Oral Gel Efficacy in Burning Mouth Syndrome	N/A
Completed	`NCT05871580` - Effect to the Photobiomodulation in the Burning Mouth Syndrome	N/A
Recruiting	`NCT05309070` - The Efficacy of N-acetyl-cysteine in the Treatment of Burning Mouth Syndrome	N/A
Completed	`NCT05399238` - Thermography and Burning Mouth Syndrome
Completed	`NCT02382029` - Acupuncture Versus Clonazepam in Burning Mouth Syndrome	Phase 0
Completed	`NCT02580734` - Efficacy of Melatonin in Burning Mouth Syndrome (BMS)	N/A
Recruiting	`NCT05819697` - Reducing Patient Memory Recall in the Burning Mouth Patient Population
Completed	`NCT02757612` - Study Evaluating the Laser Diode Effect Burning Mouth Syndrome	N/A
Completed	`NCT00862576` - A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome	N/A
Not yet recruiting	`NCT04189367` - Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine and Western Medicine	Phase 3
Completed	`NCT00001524` - Thalidomide to Treat Oral Lesions in HIV-Infected Patients	Phase 2
Recruiting	`NCT04481841` - Head Yuanshi Dian Therapy in Burning Mouth Syndrome	Early Phase 1
Completed	`NCT02686359` - Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN)	N/A