Inspiratory Muscle Training in Burned Adults

Burn Injuries Clinical Trial

— Burns  

Official title:

Effects of Adding Inspiratory Muscle Training to Pulmonary Rehabilitation Program in Adults With Burn Injuries: A Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06315712
• Other study ID #: 004201
• Status: Completed
• Phase: N/A
• Start date: January 15, 2021
• Est. completion date: September 11, 2023

Study information

• Verified date: March 2024
• Source: Qassim University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study outlines burn injury impact, emphasizes need for long-term rehabilitation. Study assesses inspiratory muscle training efficacy in improving respiratory strength, lung function, and exercise capacity in adult burn patients.

Description:

The study aimed to evaluate the effectiveness of adding inspiratory muscle training to pulmonary rehabilitation in adult burn patients. Fifty-two participants were randomly assigned to either inspiratory muscle training plus pulmonary rehabilitation or pulmonary rehabilitation alone for 8 weeks. Inspiratory muscle training consisted of using a Powerbreathe device for inspiratory muscle strengthening.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 52
• Est. completion date: September 11, 2023
• Est. primary completion date: June 16, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 49 Years

Eligibility

Inclusion Criteria:

• Burn-injured adults aged 20-49.
• Admitted to the clinic after acute treatment.
• Recovering from burns affecting at least 20% total body surface area.
• Partial or full-thickness burns.

Exclusion Criteria:

• Smokers.
• had open or unhealed wounds.
• had any known neurological deficit.
• neuromuscular diseases.
• musculoskeletal deformities.
• pulmonary diseases.
• severe cardiac problems.
• inability to participate in regular exercise.

Related Conditions & MeSH terms

• Burn Injuries
• Burns

Intervention

Other:
• inspiratory exercise
The training consisted of 6 sets of 30 breaths per day, divided into 2 sessions per day. A one-minute rest interval between each set. Training was prescribed 5 days a week for 8 weeks
• Pulmonary rehabilitation
Four resistive exercises, aerobic exercise, and deep breathing exercises, five sessions per week for 8 weeks

Locations

Country	Name	City	State
Egypt	Faculty of Physical Therapy, Cairo University	Giza	Dokki

Sponsors (2)

Lead Sponsor	Collaborator
Qassim University	Cairo University

Country where clinical trial is conducted

Egypt, 

References & Publications (3)

Gittings PM, Grisbrook TL, Edgar DW, Wood FM, Wand BM, O'Connell NE. Resistance training for rehabilitation after burn injury: A systematic literature review & meta-analysis. Burns. 2018 Jun;44(4):731-751. doi: 10.1016/j.burns.2017.08.009. Epub 2017 Oct 7 — View Citation

Ozkal O, Topuz S, Karahan S, Erdem MM, Konan A, Yasti AC. Clinical predictors of pulmonary functions, respiratory/peripheral muscle strength and exercise capacity at discharge in adults with burn injury. Disabil Rehabil. 2021 Oct;43(20):2875-2881. doi: 10.1080/09638288.2020.1720320. Epub 2020 Jan 30. — View Citation

Willis CE, Grisbrook TL, Elliott CM, Wood FM, Wallman KE, Reid SL. Pulmonary function, exercise capacity and physical activity participation in adults following burn. Burns. 2011 Dec;37(8):1326-33. doi: 10.1016/j.burns.2011.03.016. Epub 2011 May 6. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	maximal inspiratory pressure	performed using an electronic respiratory pressure meter, measures inspiratory muscle strength	At the beginning of intervention
Primary	maximal inspiratory pressure	performed using an electronic respiratory pressure meter, measures inspiratory muscle strength	After 8 weeks of intervention
Primary	maximal expiratory pressure	performed using an electronic respiratory pressure meter, assesses expiratory muscle strength.	At the beginning of intervention
Primary	maximal expiratory pressure	performed using an electronic respiratory pressure meter, assesses expiratory muscle strength.	After 8 weeks of intervention
Primary	Forced expiratory volume in 1 second	performed using a spirometer	At the beginning of intervention
Primary	Forced expiratory volume in 1 second	performed using a spirometer	After 8 weeks of intervention
Primary	forced vital capacity	performed using a spirometer	At the beginning of intervention
Primary	forced vital capacity	performed using a spirometer	After 8 weeks of intervention
Primary	Forced expiratory volume in 1 second/ forced vital capacity ratio	performed using a spirometer	At the beginning of intervention
Primary	Forced expiratory volume in 1 second/ forced vital capacity ratio	performed using a spirometer	After 8 weeks of intervention
Secondary	Functional exercise capacity	assessed using the six-minute walk test	At the beginning of intervention
Secondary	Functional exercise capacity	assessed using the six-minute walk test	After 8 weeks of intervention