Clinical Trials Logo
  1. Home
  2. Brugada Syndrome
  3. NCT04232787

Southeast Asian Brugada Syndrome Cohort — SEA-BrS  

Brugada Syndrome Clinical Trial

Official title:
Discovering the Genetic Causes of Brugada Syndrome in Thais and Southeast Asian Population

Clinical Trial Summary

Brugada syndrome (BrS) is the leading cause of sudden death in young Asian adults including Thailand. This syndrome may be hereditary and involve mutations in certain genes. Aim of the study is to identify the relationship between genetic variants and the diagnosis/clinical severity of patients with BrS.

Clinical Trial Description

This cohort study recruits BrS patients with confirmed Brugada type 1 ECG and healthy volunteers in Thailand. Data collection consists of demographic, clinical data, ECG and blood sample for genetic studies. Genotyping was done by whole genome sequencing and SNP array then compared between cases and controls. Each BrS patient will be followed up prospectively for symptoms and AICD shock. Subsequently, the study will analyze relationship between genetic variants and clinical data against clinical severity of BrS patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04232787
Study type Observational [Patient Registry]
Source Chulalongkorn University
Contact Apichai Khongphatthanayothin, MD
Phone 66891555545
Email apichaik@yahoo.com
Status Recruiting
Phase
Start date January 28, 2016
Completion date January 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05048602 - Drug-induced Brugada Syndrome Research Database
Terminated NCT00701077 - DAPERB 3,4-DiAminoPyridine and Electrophysiological Response in Brugada Syndrome Phase 3
Recruiting NCT03435393 - Ripple Mapping for Epicardial Mapping of Brugada Syndrome N/A
Active, not recruiting NCT02933437 - The Response To Ajmaline Provocation in Healthy Subjects Phase 2
Active, not recruiting NCT04257994 - Distribution of Cell-cell Junction Proteins in Arrhythmic Disorders
Recruiting NCT05685134 - Invasive and Clinical Features in Patients With Brugada Syndrome Undergoing Catheter Ablation N/A
Recruiting NCT04580992 - Defining the Electrocardiographic Effect of Propofol on the Ajmaline Provocation Drug Challenge: A Prospective Trial
Completed NCT02641431 - Epicardial Ablation in Brugada Syndrome N/A
Completed NCT03182777 - Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies N/A
Completed NCT00292032 - Registry of Unexplained Cardiac Arrest
Completed NCT04124237 - Long Term Monitoring for Risk of Sudden Death
Completed NCT02344277 - Evaluation of Subcutaneous Implantable Cardiac Defibrillator in Brugada Patients
Completed NCT04650009 - Physical Activity in Children With Inherited Cardiac Diseases
Recruiting NCT04808193 - European Perioperative Brugada Survey N/A
Recruiting NCT03491475 - Echocardiography During Ajmaline Test
Recruiting NCT05521451 - Clinical Cohort Study - TRUST
Recruiting NCT03485508 - The Brugada Syndrome: a Follow-up Study
Completed NCT00702117 - Ajmaline Utilization in the Diagnosis and Treatment of Cardiac Arrhythmias Phase 4
Recruiting NCT02704416 - Ablation in Brugada Syndrome for the Prevention of VF N/A
Recruiting NCT03775954 - Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise