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Clinical Trial Summary

The study purpose is to evaluate the morphological, functional and electrophysiological characteristics of the right ventricle before and after ajmaline in patients diagnosed with Brugada syndrome as well as to correlate CMR findings and substrate size.


Clinical Trial Description

All consecutive patients with either spontaneous or ajmaline-induced BrS-ECG pattern will be screened. A total of 30 BrS patients and 30 normal age, sex and BSA matched normal controls will be selected and enrolled. Patients will perform cardiac magnetic resonance imaging to evaluate and compare morphological and functional characteristics of the 2 groups before and after ajmaline. BrS patients will also perform a standardized programmed ventricular stimulation protocol and electroanatomical mapping to determine the substrate size. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03524079
Study type Observational
Source IRCCS Policlinico S. Donato
Contact
Status Completed
Phase
Start date April 19, 2018
Completion date November 9, 2019

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