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Lumpectomy Specimen Margin Evaluation With Tomography and Structured Light Imaging

Breast Cancer Female Clinical Trial

Official title:
Lumpectomy Specimen Margin Evaluation With Tomography and Structured Light Imaging

Clinical Trial Summary

The purpose of this study is to test a new surgical imaging system called "Structured Light Imaging (SLI)." This system is designed to examine tissue removed during breast cancer surgery to see whether the tissue's edges contain cancer. The current standard of practice is to remove the breast tumor tissue and send the tissue to the lab for analysis following surgery. One in five women (in the US) must later return for a second surgery to remove cancer cells that the lab found remaining in the tissue. In this study, researchers hope that the new SLI system may detect the cancer cells in the tissue's edges by imaging at the time of surgery. If successful, in the future we may use this system to improve entire cancer removal at the time of surgery, and reduce the need to perform a second surgery to remove additional breast tissue.

Clinical Trial Description

On the day of surgery, the surgeon will remove the patient's cancerous tissue, and then in a separate room near the operating room, imaging staff will test it with the Structured Light Imaging system. The testing may take several extra minutes to capture the images. After this imaging, the surgeon will complete the surgery. Following surgery, and per routine medical care, the patient's breast tumor tissue sample will be sent to DHMC's lab for testing. The patient will see her primary doctor for standard surgery follow-up. No additional imaging or testing will be required for this research study following the usual surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04257799
Study type Observational
Source Dartmouth-Hitchcock Medical Center
Contact
Status Completed
Phase
Start date February 6, 2020
Completion date March 16, 2022
View Details
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