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Treatment of Breakthrough Cancer Pain According to European Guidelines — BEG  

Breakthrough Cancer Pain Clinical Trial

Official title:
Adherence to Breakthrough Cancer Pain (BTcP) European Guidelines: an Observational Prospective Study.

Clinical Trial Summary

Pain is a frequent symptom in cancer patients with a negative impact on the quality of life (QoL).Breakthrough cancer pain (BTcP) is defined as "a transient exacerbation of pain, manifesting spontaneously or related to a specific predictable or unpredictable triggering factor, despite stable and adequately controlled basal pain". The present study assesses the percentage of patients who are treated according to the European guidelines (ESMO, 2018) for BTcP management in 4 European countries and the impact of the adherence to guidelines on patients' pain relief and QoL.

Clinical Trial Description

Typical BTcP episodes are of short duration (15-30 minutes/episode), moderate to severe intensity and rapid onset (maximum peak between 3-15 minutes). The best management of BTcP requires a thorough evaluation to tailor the treatment strategies. Indeed, patients with breakthrough pain should have this pain specifically assessed, starting from the appropriate diagnosis. Recently developed European guidelines support this approach and recommend treating BTcP using rapid-onset opioids (ROOs), with pharmacodynamics that mirror the quick start and short duration of the pain episode.Nevertheless, despite the drug treatment for BTcP has undergone knowledge advances in recent years and several guidelines have been published, this condition is still often inadequately managed. The present study will assess the percentage of patients who are treated according to the European guidelines for BTcP management in 4 European countries and the impact of the adherence to guidelines on patients' pain relief and QoL. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04468490
Study type Observational
Source Aziende Chimiche Riunite Angelini Francesco S.p.A
Contact
Status Terminated
Phase
Start date August 11, 2020
Completion date September 30, 2021
View Details
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