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DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease — DEBBRAH  

Brain Metastases Clinical Trial

Official title:
Multicenter, Open-Label, Single-Arm, Multicohort Phase II Clinical Trial of Trastuzumab Deruxtecan(DS-8201a) in Human Epidermal Growth Factor Receptor 2 HER2+ Advanced Breast Cancer With Brain Metastases and/or Leptomeningeal Carcinomatosis

Clinical Trial Summary

This is a multicenter, international, open-label, single-arm, multicohort, two-stage optimal Simon's design, phase II clinical trial

Clinical Trial Description

Pretreated, unresectable locally advanced or metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-positive or HER2-low expressing breast cancer (BC) with untreated or treated brain metastases (BMs) or leptomeningeal carcinomatosis (LMC). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04420598
Study type Interventional
Source MedSIR
Contact
Status Completed
Phase Phase 2
Start date May 25, 2020
Completion date April 4, 2023
View Details
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