Brain Ischemia Clinical Trial
Official title:
Neuro-anatomical Correlates on Volumetric MRI on the Impact of Brain Reserve and Cognitive Reserve on Ischemic Strokes in Elderly
Ischemic strokes are one of the leading causes of handicap and death in elderly people in
France.
Cognitive reserve (CR) is an active model, defined as a function of lifetime intellectual
activities and other environmental factors that explain differential susceptibility to
functional impairment in the presence of pathology or other neurological insult. CR is
estimated using variables for cognitive activity: years of education, professional status,
socioeconomic status… Furthermore, brain reverse (BR) is a passive and quantitative model
that depend on brain size and other quantitative aspects of the brain that explain
differential susceptibility to functional impairment in the presence of pathology.
Firstly, volume and localization of ischemic strokes have a great impact on CR and BR due to
brain injury. On the other hand, CR influences the severity and the expression of cognitive
diseases.
The investigators realize a prospective study in order to assess the impact of CR and BR on
cognitive prognosis after a right middle cerebral artery ischemic stroke in elderly patients.
n/a
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