Brain Injury Clinical Trial
Official title:
The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery,A Randomized Controlled Study
The incidence of postoperative cognitive dysfunction (POCD) is high and POCD affect the life
quality and the prognosis of patients. Geriatrics is the independent risk factor of POCD,
and POCD is also correlated with many other factors such as type of surgery, the duration of
anesthesia and the anesthesia drugs used et al. So, the prevention and treatment of POCD in
geriatrics is important.
Dexmedetomidine is found to have the effect of neuro-protection, but it is controversy
whether Dexmedetomidine has the effect of neuro-protection in geriatrics, especially the
prolonged surgery.
The purpose of this study is to explore the effect of Dexmedetomidine to the cognitive
function at prolonged surgery in geriatrics in geriatrics.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02710123 -
Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion
|
N/A | |
Recruiting |
NCT02777060 -
Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures
|
N/A | |
Completed |
NCT02262286 -
MIND (Management of Traumatic Brain Injury Diagnosis)
|
N/A | |
Completed |
NCT01461902 -
Vasospasm in Pediatric Traumatic Brain Injury
|
N/A | |
Recruiting |
NCT01198964 -
Optimization of Human Cortical Stimulation
|
||
Active, not recruiting |
NCT01207050 -
Effect of Rozerem on Sleep Among People With Traumatic Brain Injury
|
Phase 4 | |
Completed |
NCT00875329 -
Traumatic Brain Injury (TBI) Screening Instruments
|
N/A | |
Completed |
NCT01201863 -
Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy
|
Phase 4 | |
Completed |
NCT01035606 -
Training in Goal-directed Attention Regulation for Individuals With Brain Injury
|
N/A | |
Completed |
NCT01059890 -
Cerebral Antibiotics Distribution After Acute Brain Injury
|
Phase 1 | |
Completed |
NCT00571623 -
Automated Chest Physiotherapy to Improve Outcomes in Neuro
|
N/A | |
Completed |
NCT00596765 -
Neuropsychological Cognitive Behavioral Therapy for Patients With Acquired Brain Injury
|
N/A | |
Completed |
NCT00336466 -
The Erythropoietin NeuroProtective Effect: Assessment in CABG Surgery (TENPEAKS)
|
Phase 2 | |
Recruiting |
NCT05105763 -
Biofeedback Gait Retraining for Stiff Knee Gait Correction
|
N/A | |
Recruiting |
NCT02495558 -
Cough Assessment in Patients With Severe Acquired Brain Injury
|
N/A | |
Completed |
NCT02100592 -
Early Verticalization in neuroICU With ERIGO: a Safety and Feasibility Study
|
Phase 1/Phase 2 | |
Completed |
NCT00797680 -
Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest
|
Phase 2 | |
Completed |
NCT00018499 -
Genotype Influence on Recovery After Traumatic Brain Injury
|
N/A | |
Recruiting |
NCT02567201 -
Electrophysiological Evaluation of Voluntary Attention
|
N/A | |
Withdrawn |
NCT05581927 -
Whole-Body Hypothermia for Neonates With Hypoxic-Ischemic Encephalopathy(HIE)
|
N/A |