Brain Injury Clinical Trial
Official title:
The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery,A Randomized Controlled Study
The incidence of postoperative cognitive dysfunction (POCD) is high and POCD affect the life
quality and the prognosis of patients. Geriatrics is the independent risk factor of POCD,
and POCD is also correlated with many other factors such as type of surgery, the duration of
anesthesia and the anesthesia drugs used et al. So, the prevention and treatment of POCD in
geriatrics is important.
Dexmedetomidine is found to have the effect of neuro-protection, but it is controversy
whether Dexmedetomidine has the effect of neuro-protection in geriatrics, especially the
prolonged surgery.
The purpose of this study is to explore the effect of Dexmedetomidine to the cognitive
function at prolonged surgery in geriatrics in geriatrics.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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