Brain Injuries Clinical Trial
Official title:
Influence of Physical Exercise on Cognitive Functioning of Traumatic Brain Injury Patients
The aim of this study is to determine the effects of an acute session of physical exercise
on cognitive functioning and humor of traumatic brain injury patients and to investigate
whether different cognitive responses can be achieved with different intensities of exercise
(moderate and vigorous).
The investigators hypothesize that while moderate intensity physical exercise may be
beneficial to cognitive functioning, vigorous intensity may be detrimental to TBI patients,
as physical fatigue may impair alertness and other higher cognitive functions.
It is well known the benefits of physical exercise to cognitive functioning, which have been
demonstrated in animal studies and in those with healthy humans or with individuals with
some type of pathology. Nevertheless, there are few studies investigating the effects of
acute physical exercise on cognitive functions of people with traumatic brain injury, even
though they frequently have impairments in several cognitive domains due to their brain
damage.
The effect of two intensities of physical exercise (moderate and exhaustive) in attention,
processing speed, memory, executive control and decision making will be investigated in
patients with TBI. For that matter, their performance will be compared to non-brain injured
subjects submitted to the same protocol and to TBI patients submitted to a stretching
session.
Each subject will be submitted to a neuropsychological evaluation before and after the
physical exercise in order to determine if there is an improvement in cognitive performance
post-exercise.
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Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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