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Pupillometric Evaluation in Patients Declared Brain Dead - a Prospective Quality Control Study — INSPECT  

Brain Death Clinical Trial

Official title:
Investigative Neurological Study With Pupillometric Evaluation os a Clinical Tool in Patients Declared Brain Dead (INSPECT) - a Prospective Quality Control Study

Clinical Trial Summary

The aim of the study is to verify the reliability of the current purely clinical examination of the pupils (without the support of a pupillometer) in the context of clinically suspected brain death, compared to the results of a non-invasive, automated, and highly precise monocular pupillometric examination.

Clinical Trial Description

This prospective quality control study will evaluate the reliability of the clinical exam regarding pupils' reaction to light (as performed by two board certified physicians in Neurology and/or Intensive Care Medicine) as recommended by the SAMW guidelines for brain death diagnosis (SAMW-guidelines) when compared to the results of a noninvasive automated and highly-precise pupillometry in adult patients with clinically suspected brain death. Automated pupillometric measurements will be performed by the PI (RS), or the co-investigator (Dr. Pascale Grzonka) using the NeurOptics® NPi®-200 pupillometer system immediately before and after the standardized diagnostic workup for suspected brain death. In addition, demographics, clinical characteristics , treatment and laboratory data from the patients examined will be anonymously collected. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06279975
Study type Observational
Source University Hospital, Basel, Switzerland
Contact Raoul Sutter, Prof.
Phone +41 61 32 87928
Email raoul.sutter@usb.ch
Status Recruiting
Phase
Start date December 18, 2023
Completion date December 2030
View Details
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