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Clinical Trial Summary

The goal of this observational study is to identify the characteristics of brain functional connectivity in refractory constipation and fluoxetine-sensitive patients. The main questions it aims to answer are: - Investigating the alterations in brain functional connectivity in patients with refractory constipation and fluoxetine-sensitive patients - Assessing the predictive value of brain functional connectivity regarding the efficacy of fluoxetine and standard protocol treatments for constipation. Participants will receive: - Standard physiological and psychological assessments of constipation - BOLD-fMRI tests - Standard protocol and fluoxetine treatment If there is a comparison group: Researchers will compare: Refractory group/Fluoxetine sensitive group to see the specific brain alterations.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06221722
Study type Observational
Source Xijing Hospital of Digestive Diseases
Contact Zhifeng Zhao
Phone 13519171072
Email zhaozhifeng@outlook.com
Status Recruiting
Phase
Start date November 1, 2023
Completion date September 1, 2026

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