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The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury

Brain Concussion Clinical Trial

Official title:
The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury

Clinical Trial Summary

The study is a "proof-of-principle" project to examine the safety and feasibility of implementing a 1-week aerobic exercise program in the post-acute phase after mild traumatic brain injury (mTBI). The study will define the extent to which the exercise program improves recovery from mTBI in terms of relevant functional outcomes (cognition, mood, and physical status) and biomarkers (peripheral brain-derived neurotrophic factor [BDNF] concentration).

Clinical Trial Description

This is a "proof-of-principle" project for human subjects to examine the safety and feasibility of implementing a 1-week aerobic exercise program in the post-acute phase after mild traumatic brain injury (mTBI). This study will define the extent to which the exercise program improves recovery from mTBI in terms of relevant functional outcomes (cognition, mood, and physical status) and biomarkers (peripheral brain-derived neurotrophic factor [BDNF] concentration). This project will also lay the foundation for understanding the relationship between exercise and BDNF in the area of mTBI neurorecovery, thereby allowing future studies to develop best-practice methods for implementing exercise interventions as a treatment option for brain injuries. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02276079
Study type Interventional
Source University of Florida
Contact
Status Completed
Phase N/A
Start date February 17, 2015
Completion date December 22, 2016
View Details
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