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NCT02288780 Clinical Trial

Transthoracic Echocardiographic Evaluation of the Cardiac Function During Transurethral Resection of Prostate in Elderly Patients

BPH Clinical Trial

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT02288780
Other study ID # 4-2014-0734
Secondary ID
Status Terminated
Phase
First received
Last updated
Start date December 2014
Est. completion date May 1, 2015

Study information
Verified date March 2019
Source Yonsei University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Transurethral resection of the prostate (TURP) is a standard surgical treatment for benign prostatic hyperplasia (BPH). Non-conductive irrigation fluid is used to maintain good visibility of the operating field during resection of the prostate. Absorption of this hypotonic solution into the bloodstream can cause fluid overload and dilutional hyponatremia, resulting in adverse cardiovascular and central nervous system effects, transurethral resection (TUR) syndrome. BPH is common in elderly men above 60 years old. These aged people commonly have diastolic impairment by normal physiologic change without consistent symptom. This study aimed to evaluate the cardiac function focused mainly diastolic function during TURP with transthoracic echocardiography. Also, we will focus the effets of amount of irrgation fluid on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.

Recruitment information / eligibility
Status Terminated
Enrollment 2
Est. completion date May 1, 2015
Est. primary completion date May 1, 2015
Accepts healthy volunteers No
Gender Male
Age group 65 Years to 85 Years
Eligibility Inclusion Criteria:

1. Above 65years of age

2. American Society of Anesthesiologists (ASA) Physical Status I, II, III.

3. undergoing transurethral resection of the prostate(TURP)"

Exclusion Criteria:

1. severe coagulopathy or bleeding disorder(platelet count<75000, PT INR >1.2)

2. short stature (under 150 cm)

3. underwent coronary artery bypass graft

4. contraindications of regional anesthesia "

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Yonsei University

Outcome
Type Measure Description Time frame Safety issue
Primary diastolic function by TTE The participants will be followed for the duration of surgery (TURP), an expected average of 1 hour.
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