Lower Urinary Tract Symptoms Clinical Trial
Official title:
Effects of LycoComfort™ Supplementation on Symptoms Associated With Lower Urinary Tract Symptoms (LUTS)
This study will evaluate LycoComfort™ supplementation in alleviating symptoms associated with
LUTS, BPH, and general prostate concerns.
Inflammation, oxidative stress and androgenic activity in the prostate are proven catalysts
of BPH, ultimately leading to increased prostate cell proliferation. The once-daily
supplement LycoComfort™, will be under investigation for symptom relief and will be taken by
participants for a duration of 12 weeks.
LycoComfort™ is a dietary supplement containing tomato extract and phytosterols, ingredients
that have been associated with relief of symptoms associated with general prostate discomfort
and Lower Urinary Tract Symptoms (LUTS).
The purpose of this study is to evaluate changes in these symptoms after taking this
supplement daily for 12 weeks.
Although it was not until the latter part of the twenties century that investigators began to
explore the importance of lycopene, the benefits of this natural carotenoid are well studied.
A number of clinical trials have shown lycopene to be effectual for alleviating prostate
discomfort, symptoms of BPH and LUTS.
The American Urological Association estimates that 90% of men between 45 and 80 years of age
suffer some symptoms of LUTS. Several pathophysiological mechanisms are believed to lead to
LUTS and BPH, including oxidative damage, inflammation and sympathetic nervous system issues.
High blood lycopene concentrations have been suggested in epidemiological trials to be
associated with decreases in oxidative stress and contributions to disease prevention
overall. Also, clinical trials have shown that higher levels of lycopene in the blood are
associated with a reduced risk of prostate cancer, as well as other inflammatory conditions.
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