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Borderline Personality Disorder clinical trials

View clinical trials related to Borderline Personality Disorder.

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NCT ID: NCT06433843 Completed - Clinical trials for Posttraumatic Stress Disorder

FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome

Start date: January 2016
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the role FKBP5 DNA methylation levels in patients suffering from complex posttraumatic stress disorder, who participated in a 12-weeks disorder-specific DBT-PTSD inpatient treatment. DNA methylation levels were measured before and after completing DBT-PTSD.

NCT ID: NCT06076343 Completed - Clinical trials for Borderline Personality Disorder

Integrated Intervention for Borderline Personality Disorder and Caregivers

Start date: May 15, 2019
Phase: N/A
Study type: Interventional

This is a prospective, single-arm, open-label study to assess the impact of a group intervention for patients with borderline personality disorder (BPD) and a psycho-educational intervention for their caregivers. Once participants complete a comprehensive clinical assessment, the study involves the participation of those with a BPD diagnosis in Dialectical Behavior Therapy (DBT) skills training group, integrated with ongoing routine treatments. A battery of questionnaires is administered before and after the DBT skills training to assess emotion dysregulation, BPD symptoms severity and other clinical variables. Simultaneously, caregivers of individuals with BPD take part in the Family Connections (FC) program. This sub-study follows a previous pilot study conducted at the same centre. Family members complete assessment questionnaires at three different time points (i.e., at baseline, at immediately post-intervention and at a 4-month follow-up) in order to evaluate putative positive pre-post changes on burden, grief and other clinical variables. In order to explore biomarkers of BPD and stress-related neurobiological mechanisms, blood samples are collected from the BPD patient group at pre and post intervention. At baseline, a blood sample is also collected to identify stress-related biomarkers among family members.

NCT ID: NCT06074289 Completed - Family Caregivers Clinical Trials

The Impact of a Psycho-educational Program for Family Members of Individuals With Borderline Personality Disorder

Start date: December 16, 2016
Phase: N/A
Study type: Interventional

This is a prospective, single-arm, open-label study to assess the impact of the Family Connections (FC) program on various factors including burden, grief and several clinical variables (i.e., depressive symptoms, family functioning, alexithymia, global psychological distress and anger). It specifically targets caregivers of individuals diagnosed with Borderline Personality Disorder (BPD). The secondary aim of this research is to identify participant profiles that are more likely to experience improvements or deteriorations in their levels of burden and grief. In this study family members are consecutively recruited from four different Italian mental health services and undergo an assessment that includes the gathering of socio-demographic information and completing a comprehensive battery of self-report questionnaires at three specific time points (i.e., at baseline, at immediately post-intervention and at a 4-month follow-up).

NCT ID: NCT05994105 Completed - Self Esteem Clinical Trials

Integration of Augmented Reality in Expressive Art Therapy for Borderline Personality Features

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

From the last decades, applied approach for the use of augmented reality on clinical and health psychology has grown exponentially. Hence, the present study is aimed to examine the effectiveness of augmented reality for the treatment of borderline personality features in young adults. For the purpose, it is hypothesized that (i) borderline personality features of experimental groups will be reduced in posttest followed by the integration of augmented reality in expressive art therapy (ii) Borderline personality features of experimental group will decrease significantly as compared to control group in the post test followed by the integration of augmented reality in expressive art therapy (iii) Borderline personality feature of self-destruction will be reduced in posttest followed by the integration of augmented reality in expressive art therapy (iv) Borderline personality feature of affect regulation will be reduced in posttest followed by the integration of augmented reality in expressive art therapy and (v) Borderline personality feature of negative self-perception will be reduced in posttest followed by the integration of augmented reality in expressive art therapy. For the present purpose, a total of 20 subjects experiencing symptoms of Borderline personality features will be screened and recruited from the Umeed e Nau clinics of the Institute of Professional Psychology Bahria University Karachi Campus by initial screening of the subjects. Participants will be monitored through pre and post-screening of Borderline Symptoms Checklist assigned to an experimental (treatment group) and control (waiting list) group using convenient sampling. The experimental group will receive the Management plan; which will be comprised of total 14 sessions. The effectiveness of the intervention plan will be measured via quantitative measure (the latest version of SPSS).

NCT ID: NCT05831852 Completed - Clinical trials for Borderline Personality Disorder

Screening of the Possible Risk Factors for Borderline Personality Disorders and Validation of Maclean Instrument

Start date: May 1, 2023
Phase:
Study type: Observational

Borderline personality disorder is a mental illness that severely impacts a person's ability to regulate their emotions. This loss of emotional control can increase impulsivity, affect how a person feels about themselves, and negatively impact their relationships with others. In fact, the societal impact of BPDs might be found in emotional suffering, disability and economic burden. In addition in BPD, the suicide rate might be as high as 8-10%. the presence of BPD also interferes with response to treatment of physical and psychiatric comorbidities, such as migraine, HIV, anxiety disorders and substance use disorders. Furthermore, BPD in particular, are associated with high rates of unemployment, absences from work and inefficiency at work, with only 25% of patients suffering from BPD working full time and 40% receiving disability payments. Accordingly, early detection and management would be of great societal and economic impact. Our Study aim is to validate the Arabic version of Maclean Instrument for screening and detection of BPD and and investigate the possible risk factors associated with that disease

NCT ID: NCT05516238 Completed - Anxiety Disorders Clinical Trials

Systematic Use of Telepsychiatry for Outpatients

Start date: April 21, 2021
Phase: N/A
Study type: Interventional

Implementation and evaluation of video consultation in psychiatric outpatient treatment. The study will focus on patients' experiences regarding the use of VC. The study will also examine important aspects of the telepsychiatric consultation such as therapeutic alliance, consultation content, psychopathology and satisfaction levels compared to face-to-face consultations.

NCT ID: NCT05453032 Completed - Clinical trials for Borderline Personality Disorder

The Effect of Non Invasive Brain Stimulation on Impulsivity in Borderline Personality Disorder

Start date: May 10, 2021
Phase: N/A
Study type: Interventional

A pilot study to examine the effects of Non-Invasive Brain stimulation on impulsive behaviour in patients diagnosed with Borderline Personality Disorder. patients who received the neurostimulation sessions will be enrolled in short term psychotherapy (3-month)

NCT ID: NCT05428462 Completed - Clinical trials for Borderline Personality Disorder

Effectiveness of a One-day Psychoeducation Program on Internalized Stigmatization for BPD Patients

EDUC-BPD
Start date: January 1, 2021
Phase:
Study type: Observational

Education day on borderline personality disorder (BPD), including a transmission of current scientific knowledge on the disease. A dimensional understanding of BPD is delivered as well as disidentification of oneself to the symptoms of borderline personality disorder (Ducasse 2020 Eur Arch Psychiatry Clin Neurosci). The main objective is to evaluate the impact of borderline education day on self-stigma.

NCT ID: NCT05357521 Completed - Clinical trials for Borderline Personality Disorder

Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder

OXT-CORT-BPD
Start date: March 1, 2022
Phase:
Study type: Observational

This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.

NCT ID: NCT05289583 Completed - Clinical trials for Borderline Personality Disorder

Impact of Therapeutic Alliance on Dropout in a Naturalistic Sample of Patients With Borderline Pathology Receiving Residential DBT

DBT_dropout2
Start date: January 1, 2019
Phase:
Study type: Observational

Participants with Borderline pathology (≥ 3 DSM-IV-criteria) receiving an inpatient Dialectical Behavior Therapy (DBT) program completed a quality assurance questionnaire set assessing demographic information and pretreatment psychopathology during the days of their inpatient stay. Beyond that, changes of therapists were documented.