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Bone Neoplasms clinical trials

View clinical trials related to Bone Neoplasms.

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NCT ID: NCT04002817 Completed - Clinical trials for Giant Cell Tumor of Bone

Giant Cell Tumor of the Bone in Young Patients

Start date: June 5, 2019
Phase:
Study type: Observational

single institution cases series review of histological and clinical data of young patient with Giant Cell Tumors

NCT ID: NCT03979118 Completed - Advanced Cancer Clinical Trials

Exercise Prescription in Patients With Bone Metastases

Ex-Met
Start date: October 15, 2019
Phase:
Study type: Observational

Cancer which has spread to the bone, causing bone metastases (bone tumours) can weaken bone health and increase risk of fractures (breaks). Consequently, patients can be unsure whether to exercise and health professionals can be unsure what exercise advice is suitable. Despite this, it is well known that exercise improves quality-of-life for patients with bone metastases and therefore it is important that exercise is prescribed to these patients. This study aims to increase understanding of the link between daily exercise and risk of fracture in patients with bone metastases.

NCT ID: NCT03924609 Completed - Breast Cancer Clinical Trials

Impact of Intensive Follow-up for Bone Metastasis on Characteristics and Prognosis of Chinese Breast Cancer Patients

Start date: March 1, 2018
Phase:
Study type: Observational

The purpose of this study is to retrospectively collect and analyse the characteristics of breast cancer patients with bone metastasis, and compare the impact of intensive follow-up with standard post-operative surveillance on survival of Chinese breast cancer patients.

NCT ID: NCT03895216 Completed - Bone Metastases Clinical Trials

Identification and Characterization of Predictive Factors of Onset of Bone Metastases in Cancer Patients

PreMetOn
Start date: December 3, 2018
Phase:
Study type: Observational

The aim of the present study is to identify deregulated miRNAs in oncological patients with bone metastases present within the circulating exosomes and responsible for the biological mechanisms involved in the process of bone metastasis, in order to obtain a panel of biomarkers predictive of this risk. Through appropriate molecular screening methods a specific panel of significantly deregulated miRNAs will be identified; subsequently bioinformatics analyzes through the use of dedicated databases will be carried out, based on literature data and predicted protein targets in order to identify their potential role in tumor progression, and especially in the onset of bone metastases. Attention, therefore, may be focused on the individual miRNAs identified through individual analysis analyzes of gene expression. These biomarkers could also serve as therapeutic targets, allowing to improve the effectiveness of current therapies and to undertake timely and appropriate therapeutic choices, developed on the basis of the patient's molecular characteristics

NCT ID: NCT03839095 Completed - Bone Neoplasms Clinical Trials

Localized Osteosarcoma in Upper Egypt: A Clinical Prediction Model

Start date: January 1, 2018
Phase:
Study type: Observational

To assess survival outcome of pediatric patients with localized osteosarcoma of the extremities in Upper Egypt, identify factors of prognostic significance for survival, and to determine factors predictive of surgical methods employed in these patients, and developing a clinical model for risk prediction.

NCT ID: NCT03661892 Completed - Breast Cancer Clinical Trials

Pilot, Syndros, Decreasing Use of Opioids in Breast Cancer Subjects With Bone Mets

Start date: December 19, 2018
Phase: Early Phase 1
Study type: Interventional

In patients with cancer induced bone pain, addition of Syndros will improve pain relief and decrease opioid requirement.

NCT ID: NCT03547557 Completed - Bone Metastases Clinical Trials

MR Guided Focused Ultrasound Surgery in the Treatment of Pain From Bone Tumors w/ the ExAblate 2000 Strappable System

BM005
Start date: January 2007
Phase: N/A
Study type: Interventional

A Feasibility Study To Evaluate the Safety and initial Effectiveness of MR guided Focused Ultrasound Surgery in the Treatment of pain resulting from Metastatic Bone Tumors with the ExAblate 2000 strappable system.

NCT ID: NCT03404362 Completed - Bone Metastases Clinical Trials

MRgFUS Versus EBRT in Patients With Metastatic Non-spinal Bone Disease

Start date: January 2017
Phase: N/A
Study type: Interventional

The objective of this trial is to collect and compare safety and effectiveness data of Magnetic Resonance guided Focused Ultrasound (MRgFUS) using the ExAblate 2100 device and radiotherapy in the treatment of metastatic bone tumors. This study is designed as a prospective, double arm, non-randomized study with External Beam radiation therapy (EBRT) serving as control arm. The study hypothesis is that MRgFUS is an effective non-invasive and safe treatment for the palliation of metastatic bone tumors with a low incidence of co-morbidity as compared to EBRT.

NCT ID: NCT03389724 Completed - Cardiotoxicity Clinical Trials

Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia

Start date: November 14, 2017
Phase: Phase 3
Study type: Interventional

Prevention and early detection of chemotherapy-induced cardiotoxicity in children with bone tumors and Acute Myeloid Leukemia by giving capoten

NCT ID: NCT03301857 Completed - Clinical trials for Giant Cell Tumor of Bone

Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004

Start date: November 13, 2017
Phase: Phase 4
Study type: Interventional

Study 20140114 will continue to follow participants with GCTB who were treated in Study 20062004 and remained on the study at the completion of Study 20062004 for an additional 5 years on long-term safety follow up.