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Assessment of Efficacy of Zoledronic Acid in the Treatment of Bone Marrow Edema Syndrome — ZoMARS  

Bone Marrow Edema Clinical Trial

Official title:
A Prospective, Bi-centric,Randomized, Primary Double-blind, Placebo-controlled Phase III Study to Assess the Efficacy of Zoledronic Acid in the Treatment of Bone Marrow Edema Syndrome

Clinical Trial Summary

The primary aim is to test the reduction of bone marrow edema syndrome after a singular intravenous treatment with Zoledronic Acid within 6 weeks compared to placebo. The volume of the edema is defined as biometric data measured by the use of MRT before and six weeks after treatment. The hypothesis has to be checked whether Zoledronic Acid is efficient in the treatment of painful bone marrow edema. A statistically significant reduction of the edema in the MRT is considered as evidence for efficacy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01348269
Study type Interventional
Source Wuerzburg University Hospital
Contact
Status Completed
Phase Phase 3
Start date May 2011
Completion date August 26, 2015
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