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Bone Loss, Alveolar clinical trials

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NCT ID: NCT06360263 Recruiting - Bone Loss, Alveolar Clinical Trials

OSSEODENSIFICATION BY DENSAH BURS WITH ACTIVATED PLASMA ALBUMIN GEL FOR SINUS LIFTING WITH SIMULTANEOUS IMPLANT PLACEMENT

Start date: July 11, 2023
Phase: N/A
Study type: Interventional

Aim of the current study is to evaluate clinically and radiographically transcrestal sinus lifting with densah burs with the use of activated plasma albumin gel associated with simultaneous implant placement.

NCT ID: NCT05985317 Recruiting - Bone Loss, Alveolar Clinical Trials

Effect of Collagen Versus PRF on BMA Osteogenic Potential

Start date: January 25, 2023
Phase: N/A
Study type: Interventional

Utilization of collagen vs PRF membrane over the graft following sinus lift procedure and before suturing

NCT ID: NCT05887128 Recruiting - Periodontitis Clinical Trials

Accuracy of Extra-oral Bite-wing Radiography in Detecting Calculus and Crestal Bone Loss

Start date: June 1, 2023
Phase:
Study type: Observational [Patient Registry]

To compare the diagnostic accuracy of extra-oral x-rays with intra-oral x-rays, in contrast to clinically observed measurements, for the detection of calculus and bone loss of either the suprabony or infrabony types in patients undergoing periodontal surgery.

NCT ID: NCT05610748 Recruiting - Bone Loss, Alveolar Clinical Trials

Implant-supported Rehabilitation With SPAL Technique or Soft Tissue Augmentation

SPALvsSTA
Start date: July 1, 2022
Phase: Phase 4
Study type: Interventional

The primary aim of the present study is to compare the Sub-periosteal Peri-implant Augmented Layer (SPAL) technique and soft tissue augmentation (STA), performed simultaneously to implant placement, in terms of (i) implant survival rate and (ii) health/disease condition of the peri-implant tissues at 6 and 12 months following implant loading. The secondary aim of the project will be to compare the SPAL technique and STA in terms of intra- and post-operative morbidity. The study is designed as a single-blind, parallel-arm, randomized clinical trial. Patients will be recruited and treated at the Operative Unit of Dentistry, Azienda Unità€ Sanitaria Locale (A.U.S.L.) of Ferrara, Italy, and one University center (Research Centre for the Study of Periodontal and Peri-implant Diseases, University of Ferrara, Italy). Each patient will contribute the study with one sextant ("experimental sextant"). Each eligible patient will be randomly assigned to receive SPAL technique or STA according to a computer-generated randomization list. Surgical procedures will be performed by experienced periodontal and implant surgeons. Two calibrated, blinded examiners will take care of the assessment of clinical and radiographic parameters, Case Report Form (CRF) filling, as well as data extraction from CRFs for the preparation of the study database. The proportion of patients free from peri-implantitis at 12 months following loading will be the primary outcome variable of the study. The proportion of patients with complete resolution of the bone dehiscence (BD), dimensional variations and 12-months characteristics of BD, and patient-reported outcome measures will be the secondary outcomes. The design will test two hypotheses, with a non-inferiority trial in terms of primary outcome and a superiority trial in terms of secondary outcomes.

NCT ID: NCT05602493 Recruiting - Bone Loss, Alveolar Clinical Trials

A Randomized Control Trial Phase (IIIa) Unicentric, Placebo Controlled, Double-Blinded Efficacy and Safety of Topical Alendronic Acid on Alveolar Bone Remodeling After Tooth Extraction

XEOLAS
Start date: November 22, 2022
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine the efficacy and safety of the effects of a topical medication on bone remodeling after dental extraction, in order to establish whether such treatment can be a new therapeutic option for said pathology. The participation of 60 patients is expected, who will be divided randomly in equal proportions into two groups. Treatment groups: Group A (30 patients): medication administered topically. Group B (30 patients): placebo with characteristics equal to the drug under investigation.

NCT ID: NCT04835532 Recruiting - Bone Loss, Alveolar Clinical Trials

Tenting Screws in Combination With Platelet Concentrate for Vertical Alveolar Ridge Augmentation

Start date: August 10, 2021
Phase: N/A
Study type: Interventional

Alveolar bone resorption often occurs after tooth extraction. At present, guided bone regeneration technique is widely used in clinic since it leads to less trauma and less complications. Tenting screw technology, basic on the classical GBR, implants screws into the surgical area to prevent the barrier membrane from collapsing. Moreover, advanced platelet rich fibrin and injectable platelet-rich fibrin are used to provide the osteogenic function. The investigators intend to increase vertical alveolar bone augmentation by combining tenting screws and A-PRF, I-PRF.

NCT ID: NCT03927937 Recruiting - Tooth Loss Clinical Trials

Tooth Autotransplantation and Bone Dimension Changes

Start date: December 5, 2018
Phase: N/A
Study type: Interventional

Tooth autotransplantation is a treatment option to replace tooth with imposible prognosis. In several cases the receipt site has a reduced bone dimension. This situation may be imposible the treatment with dental implants without bone reconstruction. Autotransplantation seem to improve the anatomic characteristic of the receipt site without any reconstruction approach. The aim of this study is to evaluate the bone dimension changes followed autotransplantation treatment.

NCT ID: NCT03855852 Recruiting - Bone Loss, Alveolar Clinical Trials

Evaluation of Vertical Bone Gain After Ridge Augmentation With APRF & Xenograft Vs Collagen Membrane & Xenograft. RCT

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Comparative study for evaluation of vertical bone gain after one stage ridge augmentation with advanced platelet rich fibrin (A-PRF) and xenograft versus guided bone regeneration using collagen membrane and xenograft.

NCT ID: NCT03528330 Recruiting - Clinical trials for Dental Implant Failed

Clinical, Radiological and Microbiological Outcomes of Implants With Two Different Connection Configurations, a Split-mouth RCT.

Start date: January 8, 2018
Phase: N/A
Study type: Interventional

This study designed as a randomized controlled split-mouth trial will be conducted at the Dental Clinic of the University of Valencia. The aim will be to assess differences in clinical, radiological and microbiological outcomes between implants with 2 different connections: internal hexagon and conical connection. Following the premises, to minimize the bias related to prosthetic phase and maximize the effect of connections on MBL changes, a 1abutment-1time protocol will be used. The study hypothesis is that there will be no statistically significant differences between both implant connections.

NCT ID: NCT03524872 Recruiting - Bone Loss, Alveolar Clinical Trials

Implant/Abutment Module Stability of Original vs Compatible Connections

Start date: January 8, 2018
Phase: N/A
Study type: Interventional

Together with materials and type of retention, the stability of the implant abutment connection represents one of the key factor for the success rate of an implant supported restoration. The recent diffusion of high quality and easy to use CAD/CAM systems has contributed to market launch of a number of competing companies that offer the so called "clonical" or "compatible" restorative components. Although they are claimed to be identical, the original abutments are supposed to present maximum accuracy and consequently lower microleakage. The aim of the present randomized controlled trial will be to analyze the implant abutment junction stability comparing implant-supported crowns restored with original components and compatible non-original abutments. The hypothesis is that original components will present significantly better stability than non-original abutments.