Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women

Bone Disease, Metabolic Clinical Trial

Official title: Effect of Calcium and Vitamin D Supplements and/or Prunes on Bone Health

Status Recruiting

Clinical Trial Summary

The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women.

Clinical Trial Description

Two hundred randomly assigned to one of two treatment groups: 1) 30 g prunes and 2) control (0 g prunes). Both groups received 500 mg calcium and 400 IU Vitamin D as a daily supplement. Blood samples are collected at baseline, 12 and 24 months to assess biomarkers of bone turnover. Physical activity recall and food records are obtained at baseline, 12 and 24 months to examine physical activity and dietary confounders as potential covariates. Dual-energy x-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) will be completed at baseline, 12 and 24 months to examine bone mineral density and structure. ;

Related Conditions & MeSH terms

• Bone Disease, Metabolic
• Bone Diseases
• Bone Diseases, Metabolic
• Metabolic Diseases

• NCT number: NCT06184646
• Study type: Interventional
• Source: San Diego State University
• Contact: Shirin Hooshmand, PhD
• Phone: 619-594-6823
• Email: shooshmand@sdsu.edu
• Status: Recruiting
• Phase: N/A
• Start date: March 15, 2024
• Completion date: December 2028