Attentional Bias in Body Dysmorphic Disorder

Body Dysmorphic Disorders Clinical Trial

— VAB  

Official title:

Attentional Bias in Body Dysmorphic Disorder

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01398904
• Other study ID #: 2010P002912
• Status: Completed
• Phase: N/A
• First received: July 15, 2011
• Last updated: December 2, 2014
• Start date: March 2011
• Est. completion date: July 2012

Study information

• Verified date: December 2014
• Source: Massachusetts General Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Body Dysmorphic Disorder (BDD) participants will demonstrate greater attentional biases as compared to healthy control (HC) participants. Greater attention bias will be associated with greater distress. Greater attention bias will be associated with greater symptom severity.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 51
• Est. completion date: July 2012
• Est. primary completion date: July 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria for BDD and healthy control participants:

• males and females 18 years of age or older

• sufficient fluency of English to understand study staff, procedures, and questionnaires

• ability to provide informed consent

Inclusion for BDD participants only;

• primary diagnosis of Diagnostic and Statistical Manual 4th Edition (DSM-IV-TR) BDD

• BDD Yale-Brown Obsessive Compulsive Disorder score (Y-BOCS) of > 20

• primary facial/head concern

Exclusion Criteria:

• Major medical or neurological conditions

• schizophrenia, schizoaffective disorder, or any other current lifetime DSM-IV psychotic disorder that is not attributable to delusional BDD

• current suicidality

• current homicidality

Exclusion criteria for healthy controls:

• Any current Axis I psychiatric illness

• history of BDD

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Body Dysmorphic Disorders

Locations

Country	Name	City	State
United States	Massachusetts General Hospital	Boston	Massachusetts

Sponsors (1)

Lead Sponsor	Collaborator
Massachusetts General Hospital

Country where clinical trial is conducted

United States, 

References & Publications (10)

Carey P, Seedat S, Warwick J, van Heerden B, Stein DJ. SPECT imaging of body dysmorphic disorder. J Neuropsychiatry Clin Neurosci. 2004 Summer;16(3):357-9. — View Citation

Deckersbach T, Savage CR, Phillips KA, Wilhelm S, Buhlmann U, Rauch SL, Baer L, Jenike MA. Characteristics of memory dysfunction in body dysmorphic disorder. J Int Neuropsychol Soc. 2000 Sep;6(6):673-81. — View Citation

Janelle CM, Hausenblas HA, Fallon EA, Gardner RE. A visual search examination of attentional biases among individuals with high and low drive for thinness. Eat Weight Disord. 2003 Jun;8(2):138-44. — View Citation

Kelly MM, Walters C, Phillips KA. Social anxiety and its relationship to functional impairment in body dysmorphic disorder. Behav Ther. 2010 Jun;41(2):143-53. doi: 10.1016/j.beth.2009.01.005. Epub 2009 Oct 7. — View Citation

Maner JK, Holm-Denoma JM, Van Orden KA, Gailliot MT, Gordon KH, Joiner TE Jr. Evidence for attentional bias in women exhibiting bulimotypic symptoms. Int J Eat Disord. 2006 Jan;39(1):55-61. — View Citation

Phillips KA, Coles ME, Menard W, Yen S, Fay C, Weisberg RB. Suicidal ideation and suicide attempts in body dysmorphic disorder. J Clin Psychiatry. 2005 Jun;66(6):717-25. — View Citation

Phillips KA, Menard W, Fay C, Pagano ME. Psychosocial functioning and quality of life in body dysmorphic disorder. Compr Psychiatry. 2005 Jul-Aug;46(4):254-60. — View Citation

Phillips KA. Quality of life for patients with body dysmorphic disorder. J Nerv Ment Dis. 2000 Mar;188(3):170-5. — View Citation

Roefs A, Jansen A, Moresi S, Willems P, van Grootel S, van der Borgh A. Looking good. BMI, attractiveness bias and visual attention. Appetite. 2008 Nov;51(3):552-5. doi: 10.1016/j.appet.2008.04.008. Epub 2008 Apr 15. — View Citation

Savage CR, Baer L, Keuthen NJ, Brown HD, Rauch SL, Jenike MA. Organizational strategies mediate nonverbal memory impairment in obsessive-compulsive disorder. Biol Psychiatry. 1999 Apr 1;45(7):905-16. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Attention Pattern	Gaze tracking via an Eyelink II eye tracker will determine perception of visual information.	Day 2	No
Secondary	Subjective Units of Distress Scale (SUDS)	Participants will provide a distress score based on the facial images observed.	Day 2	No
Secondary	Facial Attractiveness	Using a 9-point Likert scale, participants will rate the perceived most attractive and unattractive feature of their own and the control face.	Day 2	No