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Effect of Indication Based Blood Product Transfusion in Patients Undergoing Major Oncological Surgery

Blood Transfusion Clinical Trial

Official title:
A Multi-center, Single Blinded Randomized Trial Investigating Indications Based Blood Transfusion Practices in Patients With Major Oncological Surgery

Clinical Trial Summary

Investigators aimed to compare the effect on different indications (blood volume loss based VS hemoglobin concentration based ) based blood transfusion practices in patients undergoing major oncological surgery for pelvic or spinal tumor and investigate their postoperative complications.

Clinical Trial Description

260 patients underwent major oncological surgery for open pelvic or spinal tumor resection were included in this study. We looked at white blood cells, hemoglobin, hematocrit, neutrophil ratio, C-reactive protein, erythrocyte sedimentation rate, and IL-6 levels 1 day, 3 days, and 7 days after surgery The main question it sought to answer was whether there was a difference in postoperative complications 30 days after surgery between patients who received blood transfusions based on volume loss and those who received blood transfusions based on hemoglobin concentration during surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05607940
Study type Interventional
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact Xiaobo Yan, MD
Phone 13588153306
Email yanxiaobo82@zju.edu.cn
Status Not yet recruiting
Phase Phase 2/Phase 3
Start date January 2023
Completion date December 2025
View Details
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