Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair

Blood Pressure Clinical Trial

— COMPETENT  

Official title:

Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04865614
• Other study ID #: COMPETENT
• Status: Completed
• Start date: April 1, 2019
• Est. completion date: December 1, 2020

Study information

• Verified date: October 2021
• Source: Heidelberg University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The induction of anaesthesia is one of the most critical situations for high-risk-patients undergoing interventions surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this phase.

This retrospective cohort study aims to find out if the choice of the induction agent has a major impact on blood pressure and the use of catecholamines during the induction and the interventional procedure in patients undergoing interventional mitral valve repair.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 57
• Est. completion date: December 1, 2020
• Est. primary completion date: December 1, 2020
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients undergoing elective interventional mitral valve repair

• Sevoflurane or etomidate have been used for induction of anesthesia

Exclusion Criteria:

• Pregnancy

Related Conditions & MeSH terms

• Blood Pressure
• Hypotension
• Hypotension Drug-Induced

Intervention

Drug:
• Etomidate
Use of etomidate
• Sevoflurane
Use of sevoflurane

Locations

Country	Name	City	State
Germany	Anästhesiologische Klinik (Universitätsklinikum Heidelberg)	Heidelberg	Baden-Würtemberg

Sponsors (2)

Lead Sponsor	Collaborator
Heidelberg University	University Hospital, Essen

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Post-induction hypotension	Hypotension in the first 20 minutes after induction of anesthesia	First 20 minutes after induction of anaesthesia
Secondary	Use of catecholamines after induction during the first 20 minutes after inductionafter induction	Use of catecholamines during the first 20 minutes after induction of anaesthesia	First 20 minutes after induction
Secondary	Use of catecholamines	Use of catecholamines during the procedure	Length of procedure (Approximately 60 to 90 minutes in average)